Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE0WGR8)

• DME Name: Phenylalanine--tRNA ligase mitochondrial (FARS2) DME Info
• Gene Name: FARS2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	5.87E-01	1.16E-01	3.19E-01
Alopecia	ED70	Skin from scalp	4.76E-01	5.54E-03	1.34E-02
Alzheimer's disease	8A20	Entorhinal cortex	2.75E-05	-1.85E-01	-5.40E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.01E-02	1.01E-01	8.93E-01
Aortic stenosis	BB70	Calcified aortic valve	4.75E-01	-2.07E-01	-2.56E-01
Apnea	7A40	Hyperplastic tonsil	5.01E-01	-2.56E-01	-3.47E-01
Arthropathy	FA00-FA5Z	Peripheral blood	4.49E-02	-2.51E-01	-1.35E+00
Asthma	CA23	Nasal and bronchial airway	1.61E-02	1.66E-01	2.25E-01
Atopic dermatitis	EA80	Skin	3.32E-01	6.93E-02	2.04E-01
Autism	6A02	Whole blood	1.40E-03	-2.84E-01	-1.01E+00
Autoimmune uveitis	9A96	Peripheral monocyte	3.09E-01	-1.04E-01	-5.84E-01
Autosomal dominant monocytopenia	4B04	Whole blood	7.30E-01	-5.87E-02	-3.04E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.78E-01	-7.48E-02	-2.67E-01
Batten disease	5C56.1	Whole blood	5.55E-01	-1.87E-01	-1.36E+00
Behcet's disease	4A62	Peripheral blood	6.18E-01	-1.31E-01	-6.96E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	4.42E-01	2.40E-02	6.26E-02
Bladder cancer	2C94	Bladder tissue	1.45E-07	-5.13E-01	-3.57E+00
Breast cancer	2C60-2C6Z	Breast tissue	2.87E-04	1.87E-01	3.19E-01
Cardioembolic stroke	8B11.20	Whole blood	9.89E-01	-4.57E-02	-1.79E-01
Cervical cancer	2C77	Cervical tissue	5.62E-01	-1.74E-01	-3.76E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	8.31E-01	-1.51E-01	-1.31E-01
Chronic hepatitis C	1E51.1	Whole blood	2.96E-01	-1.06E-01	-6.11E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	3.88E-01	-5.49E-02	-2.11E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.78E-02	1.16E-01	4.79E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	3.00E-02	-5.67E-01	-1.15E+00
Colon cancer	2B90	Colon tissue	2.64E-02	7.49E-02	2.42E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.94E-01	5.42E-02	9.42E-02
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	6.27E-01	8.42E-02	1.55E-01
Endometriosis	GA10	Endometrium tissue	3.45E-01	-2.35E-01	-3.90E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.45E-02	1.43E-01	9.28E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.94E-04	9.01E-01	1.70E+00
Gastric cancer	2B72	Gastric tissue	4.27E-01	3.67E-01	4.16E-01
Glioblastopma	2A00.00	Nervous tissue	1.46E-87	7.36E-01	1.25E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	4.74E-01	5.17E-01	6.50E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.87E-04	1.03E+00	1.88E+00
Head and neck cancer	2D42	Head and neck tissue	3.13E-01	2.52E-02	4.79E-02
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	5.72E-01	-1.37E-01	-4.68E-01
Huntington's disease	8A01.10	Whole blood	9.45E-01	1.83E-01	4.26E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.11E-01	1.89E-01	1.09E+00
Immunodeficiency	4A00-4A20	Peripheral blood	1.13E-03	2.58E-01	2.07E+00
Influenza	1E30	Whole blood	7.69E-02	-8.03E-01	-1.98E+00
Interstitial cystitis	GC00.3	Bladder tissue	2.22E-02	8.23E-02	1.47E+00
Intracranial aneurysm	8B01.0	Intracranial artery	8.70E-01	-9.29E-02	-4.02E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	5.08E-02	-1.15E-01	-2.16E-01
Ischemic stroke	8B11	Peripheral blood	5.09E-01	5.91E-02	3.12E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.74E-10	-5.08E-01	-1.12E+00
Lateral sclerosis	8B60.4	Skin	1.81E-02	3.68E-01	2.40E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	5.32E-01	-4.99E-02	-1.57E-01
Liver cancer	2C12.0	Liver tissue	6.35E-01	5.67E-02	2.09E-01
Liver failure	DB99.7-DB99.8	Liver tissue	9.18E-02	-3.56E-01	-1.07E+00
Lung cancer	2C25	Lung tissue	2.10E-03	-6.62E-02	-1.91E-01
Lupus erythematosus	4A40	Whole blood	2.27E-01	5.69E-02	1.04E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	6.32E-01	-3.69E-02	-1.18E-01
Major depressive disorder	6A70-6A7Z	Whole blood	8.22E-02	-8.23E-02	-1.86E-01
Melanoma	2C30	Skin	6.01E-02	2.20E-01	4.30E-01
Multiple myeloma	2A83.1	Peripheral blood	3.11E-01	-8.43E-02	-4.15E-01
Multiple myeloma	2A83.1	Bone marrow	1.61E-04	5.48E-01	1.80E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	6.57E-01	2.35E-02	7.78E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	4.62E-02	-2.11E-01	-3.63E-01
Myelofibrosis	2A20.2	Whole blood	5.72E-02	-2.35E-01	-1.92E+00
Myocardial infarction	BA41-BA50	Peripheral blood	9.82E-04	-5.87E-01	-6.69E-01
Myopathy	8C70.6	Muscle tissue	8.86E-03	-1.77E-01	-9.47E-01
Neonatal sepsis	KA60	Whole blood	3.69E-15	-6.04E-01	-1.60E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.72E-06	2.17E+00	3.76E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.22E-02	1.88E-01	1.03E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.74E-01	-8.23E-02	-3.27E-01
Olive pollen allergy	CA08.00	Peripheral blood	7.24E-01	4.72E-02	6.12E-02
Oral cancer	2B6E	Oral tissue	4.46E-05	9.69E-01	1.14E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.58E-01	5.36E-02	6.57E-02
Osteoporosis	FB83.1	Bone marrow	3.94E-03	-3.90E-01	-1.92E+00
Ovarian cancer	2C73	Ovarian tissue	2.77E-03	9.09E-01	1.44E+00
Pancreatic cancer	2C10	Pancreas	1.17E-01	1.92E-01	7.20E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	1.42E-01	-4.02E-01	-8.90E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.35E-01	-1.28E-01	-8.24E-01
Pituitary cancer	2D12	Pituitary tissue	2.17E-02	4.91E-01	8.01E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.48E-01	3.53E-01	8.77E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	3.94E-01	1.13E-01	4.10E-01
Polycythemia vera	2A20.4	Whole blood	6.40E-15	-3.54E-01	-2.60E+00
Pompe disease	5C51.3	Biceps muscle	5.92E-01	-1.65E-01	-4.39E-01
Preterm birth	KA21.4Z	Myometrium	3.24E-01	2.07E-01	1.21E+00
Prostate cancer	2C82	Prostate	5.22E-01	1.88E-01	2.22E-01
Psoriasis	EA90	Skin	2.72E-02	-7.32E-02	-2.22E-01
Rectal cancer	2B92	Rectal colon tissue	2.04E-01	-1.93E-02	-1.82E-01
Renal cancer	2C90-2C91	Kidney	4.10E-02	1.27E-01	1.52E-01
Retinoblastoma	2D02.2	Uvea	1.47E-01	3.12E-01	1.30E+00
Rheumatoid arthritis	FA20	Synovial tissue	2.60E-02	8.83E-01	1.45E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	8.52E-01	3.29E-02	9.73E-02
Schizophrenia	6A20	Prefrontal cortex	5.95E-01	-1.62E-02	-2.63E-02
Schizophrenia	6A20	Superior temporal cortex	8.21E-01	-8.13E-03	-3.87E-02
Scleroderma	4A42.Z	Whole blood	4.57E-02	-1.59E-01	-1.15E+00
Seizure	8A60-8A6Z	Whole blood	6.48E-01	8.37E-02	2.96E-01
Sensitive skin	EK0Z	Skin	6.47E-01	-1.47E-02	-6.97E-02
Sepsis with septic shock	1G41	Whole blood	1.88E-53	-7.56E-01	-2.06E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.41E-01	-3.86E-01	-9.69E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.13E-02	1.14E+00	1.87E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.05E-01	5.10E-02	1.80E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.86E-01	-1.49E-01	-8.53E-01
Skin cancer	2C30-2C3Z	Skin	9.13E-01	1.64E-02	4.31E-02
Thrombocythemia	3B63	Whole blood	2.64E-04	-2.10E-01	-1.70E+00
Thrombocytopenia	3B64	Whole blood	7.02E-01	3.48E-01	3.72E-01
Thyroid cancer	2D10	Thyroid	6.07E-20	-3.79E-01	-1.75E+00
Tibial muscular dystrophy	8C75	Muscle tissue	2.73E-02	-2.43E-01	-7.43E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.29E-03	-4.57E-01	-3.39E+00
Type 2 diabetes	5A11	Liver tissue	3.25E-01	8.70E-02	7.77E-01
Ureter cancer	2C92	Urothelium	7.41E-01	2.34E-02	1.19E-01
Uterine cancer	2C78	Endometrium tissue	4.54E-01	-2.29E-02	-4.18E-02
Vitiligo	ED63.0	Skin	9.23E-03	-1.53E-01	-7.66E-01