Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE6AY40)

• DME Name: N-acetyl-beta-glucosaminidase beta (HEXB) DME Info
• Gene Name: HEXB

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.50E-03	1.14E-01	2.94E-01
Alopecia	ED70	Skin from scalp	5.32E-06	-2.63E-01	-8.64E-01
Alzheimer's disease	8A20	Entorhinal cortex	8.81E-01	4.38E-02	1.61E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.27E-01	1.28E-01	6.86E-01
Aortic stenosis	BB70	Calcified aortic valve	7.91E-01	1.66E-01	1.18E-01
Apnea	7A40	Hyperplastic tonsil	9.43E-01	8.21E-02	1.56E-01
Arthropathy	FA00-FA5Z	Peripheral blood	7.78E-01	4.33E-02	2.44E-01
Asthma	CA23	Nasal and bronchial airway	9.82E-05	4.44E-01	7.17E-01
Atopic dermatitis	EA80	Skin	2.62E-13	-5.29E-01	-2.32E+00
Autism	6A02	Whole blood	1.37E-03	4.17E-01	9.89E-01
Autoimmune uveitis	9A96	Peripheral monocyte	2.13E-01	-1.52E-01	-2.15E-01
Autosomal dominant monocytopenia	4B04	Whole blood	4.70E-01	-1.41E-01	-4.23E-01
Bacterial infection of gingival	1C1H	Gingival tissue	3.18E-11	3.76E-01	1.16E+00
Batten disease	5C56.1	Whole blood	9.96E-01	1.52E-01	4.52E-01
Behcet's disease	4A62	Peripheral blood	4.91E-01	1.07E-01	4.52E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	7.72E-01	1.74E-02	4.84E-02
Bladder cancer	2C94	Bladder tissue	3.52E-13	-7.88E-01	-6.70E+00
Breast cancer	2C60-2C6Z	Breast tissue	8.48E-01	-1.79E-02	-3.22E-02
Cardioembolic stroke	8B11.20	Whole blood	1.17E-02	1.02E-01	6.79E-01
Cervical cancer	2C77	Cervical tissue	3.75E-03	5.27E-01	1.18E+00
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.22E-01	1.73E-02	5.58E-02
Chronic hepatitis C	1E51.1	Whole blood	6.96E-01	-2.76E-01	-5.73E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.77E-01	-2.03E-02	-5.92E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	8.97E-02	8.68E-02	2.96E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	7.55E-01	-1.72E-01	-4.07E-01
Colon cancer	2B90	Colon tissue	8.33E-07	1.32E-01	6.49E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.02E-01	3.88E-01	1.00E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	3.79E-01	7.84E-02	1.90E-01
Endometriosis	GA10	Endometrium tissue	6.49E-02	-1.35E-01	-1.48E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.33E-02	-1.20E-01	-7.31E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.05E-16	1.50E+00	1.94E+00
Gastric cancer	2B72	Gastric tissue	3.44E-02	6.61E-01	3.03E+00
Glioblastopma	2A00.00	Nervous tissue	1.01E-76	6.75E-01	1.37E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	3.61E-01	-2.58E-01	-1.17E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	5.05E-01	2.92E-01	3.79E-01
Head and neck cancer	2D42	Head and neck tissue	1.70E-26	6.51E-01	1.80E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.50E-01	2.61E-01	5.89E-01
Huntington's disease	8A01.10	Whole blood	7.97E-01	-1.45E-01	-2.38E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	6.19E-02	2.37E-01	1.26E+00
Immunodeficiency	4A00-4A20	Peripheral blood	8.92E-01	3.79E-02	2.97E-01
Influenza	1E30	Whole blood	9.11E-01	5.82E-03	3.94E-02
Interstitial cystitis	GC00.3	Bladder tissue	6.07E-03	2.59E-01	3.40E+00
Intracranial aneurysm	8B01.0	Intracranial artery	8.93E-05	9.61E-01	4.73E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	5.14E-02	-4.81E-02	-4.08E-01
Ischemic stroke	8B11	Peripheral blood	5.61E-01	-7.39E-02	-2.69E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.61E-04	-2.09E-01	-7.31E-01
Lateral sclerosis	8B60.4	Skin	2.15E-01	1.58E-01	1.16E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	4.16E-01	5.48E-02	6.30E-02
Liver cancer	2C12.0	Liver tissue	1.08E-08	5.08E-01	1.25E+00
Liver failure	DB99.7-DB99.8	Liver tissue	2.40E-03	3.84E-01	1.55E+00
Lung cancer	2C25	Lung tissue	1.01E-25	-3.39E-01	-8.87E-01
Lupus erythematosus	4A40	Whole blood	1.41E-10	3.51E-01	8.56E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	6.35E-01	-4.88E-02	-1.35E-01
Major depressive disorder	6A70-6A7Z	Whole blood	2.30E-01	5.55E-02	2.72E-01
Melanoma	2C30	Skin	4.90E-04	4.83E-01	9.40E-01
Multiple myeloma	2A83.1	Peripheral blood	3.51E-01	-1.00E-01	-5.59E-01
Multiple myeloma	2A83.1	Bone marrow	2.51E-05	1.70E+00	3.78E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.42E-01	-1.41E-01	-4.36E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.68E-02	6.21E-02	1.80E-01
Myelofibrosis	2A20.2	Whole blood	7.67E-04	-4.04E-01	-2.08E+00
Myocardial infarction	BA41-BA50	Peripheral blood	1.23E-01	2.34E-01	3.47E-01
Myopathy	8C70.6	Muscle tissue	1.50E-05	6.88E-01	2.82E+00
Neonatal sepsis	KA60	Whole blood	2.34E-12	5.55E-01	1.13E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.66E-08	1.34E+00	3.78E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	3.55E-01	-1.27E-01	-7.99E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.06E-01	2.94E-03	1.61E-02
Olive pollen allergy	CA08.00	Peripheral blood	2.47E-01	7.66E-01	8.70E-01
Oral cancer	2B6E	Oral tissue	1.70E-05	7.07E-01	9.72E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	8.96E-01	-2.57E-01	-3.18E-01
Osteoporosis	FB83.1	Bone marrow	2.57E-02	-5.88E-01	-2.93E+00
Ovarian cancer	2C73	Ovarian tissue	5.31E-02	1.86E-01	5.77E-01
Pancreatic cancer	2C10	Pancreas	6.09E-04	5.26E-01	1.44E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	7.63E-01	-3.27E-02	-6.35E-02
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.37E-05	4.33E-01	1.20E+00
Pituitary cancer	2D12	Pituitary tissue	2.16E-01	1.78E-01	4.74E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	9.40E-01	3.60E-02	1.18E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	5.55E-01	-7.98E-03	-5.01E-02
Polycythemia vera	2A20.4	Whole blood	1.32E-04	-2.14E-01	-1.05E+00
Pompe disease	5C51.3	Biceps muscle	3.77E-07	1.47E+00	5.84E+00
Preterm birth	KA21.4Z	Myometrium	4.11E-01	-2.99E-01	-1.29E+00
Prostate cancer	2C82	Prostate	1.38E-02	-1.29E-01	-3.78E-01
Psoriasis	EA90	Skin	7.87E-04	-8.87E-02	-3.15E-01
Rectal cancer	2B92	Rectal colon tissue	1.09E-01	-1.16E-01	-4.83E-01
Renal cancer	2C90-2C91	Kidney	9.50E-04	9.34E-01	1.58E+00
Retinoblastoma	2D02.2	Uvea	3.54E-12	2.32E+00	1.85E+01
Rheumatoid arthritis	FA20	Synovial tissue	1.91E-02	9.84E-01	1.36E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.01E-01	-2.87E-02	-1.97E-01
Schizophrenia	6A20	Prefrontal cortex	3.03E-01	3.07E-02	3.27E-02
Schizophrenia	6A20	Superior temporal cortex	6.02E-01	4.65E-02	2.24E-01
Scleroderma	4A42.Z	Whole blood	3.51E-02	1.36E-01	1.05E+00
Seizure	8A60-8A6Z	Whole blood	7.77E-01	2.08E-01	5.11E-01
Sensitive skin	EK0Z	Skin	9.22E-01	5.20E-02	3.88E-01
Sepsis with septic shock	1G41	Whole blood	1.80E-08	2.32E-01	4.90E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.49E-01	-7.21E-01	-2.12E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.62E-02	-7.40E-01	-8.89E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	4.19E-01	1.72E-01	8.31E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	9.30E-01	-1.09E-01	-4.25E-01
Skin cancer	2C30-2C3Z	Skin	8.33E-06	2.34E-01	7.65E-01
Thrombocythemia	3B63	Whole blood	2.61E-03	-3.69E-01	-1.82E+00
Thrombocytopenia	3B64	Whole blood	4.66E-01	-4.34E-01	-7.08E-01
Thyroid cancer	2D10	Thyroid	7.16E-05	6.46E-02	2.70E-01
Tibial muscular dystrophy	8C75	Muscle tissue	3.70E-07	5.90E-01	2.59E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	9.59E-01	-1.75E-01	-2.65E+00
Type 2 diabetes	5A11	Liver tissue	5.67E-02	2.72E-01	1.24E+00
Ureter cancer	2C92	Urothelium	8.05E-01	-4.07E-02	-5.43E-02
Uterine cancer	2C78	Endometrium tissue	2.39E-05	2.50E-01	3.88E-01
Vitiligo	ED63.0	Skin	5.84E-01	1.19E-02	5.28E-02