Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DE8DJ3N)

• DME Name: Nicotinamide riboside kinase 2 (NRK2) DME Info
• Gene Name: NMRK2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.18E-03	8.11E-02	2.81E-01
Alopecia	ED70	Skin from scalp	5.38E-05	-1.84E-01	-8.24E-01
Alzheimer's disease	8A20	Entorhinal cortex	3.79E-01	-3.45E-02	-1.82E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.62E-02	4.54E-01	1.12E+00
Aortic stenosis	BB70	Calcified aortic valve	4.31E-01	1.42E-01	5.15E-01
Apnea	7A40	Hyperplastic tonsil	2.26E-01	-1.61E-01	-6.15E-01
Arthropathy	FA00-FA5Z	Peripheral blood	3.93E-01	6.76E-02	4.42E-01
Asthma	CA23	Nasal and bronchial airway	1.02E-01	-8.54E-02	-2.14E-01
Atopic dermatitis	EA80	Skin	1.69E-03	-9.54E-02	-8.06E-01
Autism	6A02	Whole blood	6.67E-02	-2.21E-01	-6.46E-01
Autoimmune uveitis	9A96	Peripheral monocyte	9.88E-04	-2.76E-01	-2.10E+00
Autosomal dominant monocytopenia	4B04	Whole blood	1.19E-01	-1.12E-01	-7.61E-01
Bacterial infection of gingival	1C1H	Gingival tissue	9.66E-02	1.01E-01	3.56E-01
Batten disease	5C56.1	Whole blood	1.33E-01	6.40E-02	5.95E-01
Behcet's disease	4A62	Peripheral blood	4.64E-01	5.27E-02	3.08E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	3.79E-01	-4.09E-02	-2.28E-01
Bladder cancer	2C94	Bladder tissue	1.74E-03	5.37E-01	1.95E+00
Breast cancer	2C60-2C6Z	Breast tissue	4.07E-04	-5.33E-02	-1.30E-01
Cardioembolic stroke	8B11.20	Whole blood	6.06E-01	1.47E-02	6.63E-02
Cervical cancer	2C77	Cervical tissue	4.00E-03	1.35E-01	9.28E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.81E-01	-7.07E-02	-2.65E-01
Chronic hepatitis C	1E51.1	Whole blood	4.69E-01	0.00E+00	0.00E+00
Chronic obstructive pulmonary disease	CA22	Lung tissue	8.76E-02	6.78E-02	3.00E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.95E-04	2.95E-01	1.01E+00
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	4.69E-01	-1.35E-02	-1.36E-01
Colon cancer	2B90	Colon tissue	2.63E-06	-1.06E-01	-3.50E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	4.04E-01	-1.74E-01	-7.73E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.81E-01	1.61E-02	7.11E-02
Endometriosis	GA10	Endometrium tissue	1.04E-01	2.78E-01	6.88E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	2.54E-01	1.69E-01	7.08E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.78E-02	-2.51E-01	-9.32E-01
Gastric cancer	2B72	Gastric tissue	2.87E-01	-4.74E-01	-1.33E+00
Glioblastopma	2A00.00	Nervous tissue	9.05E-30	-2.35E-01	-5.92E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	1.80E-01	3.46E-02	9.70E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	9.28E-06	-9.44E-01	-2.60E+00
Head and neck cancer	2D42	Head and neck tissue	1.37E-01	5.97E-02	6.96E-02
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.49E-01	-1.86E-02	-8.71E-02
Huntington's disease	8A01.10	Whole blood	9.09E-02	1.54E-01	1.10E+00
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	8.42E-01	1.45E-02	7.52E-02
Immunodeficiency	4A00-4A20	Peripheral blood	6.16E-01	6.26E-03	5.18E-02
Influenza	1E30	Whole blood	4.91E-03	4.18E-01	3.36E+00
Interstitial cystitis	GC00.3	Bladder tissue	4.70E-02	2.09E-01	2.47E+00
Intracranial aneurysm	8B01.0	Intracranial artery	6.21E-04	-8.44E-01	-1.30E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.81E-01	7.68E-02	2.35E-01
Ischemic stroke	8B11	Peripheral blood	8.05E-01	1.64E-02	1.23E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.25E-01	9.62E-03	2.78E-02
Lateral sclerosis	8B60.4	Skin	7.25E-01	-3.74E-02	-1.76E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	2.15E-02	2.56E-01	8.72E-01
Liver cancer	2C12.0	Liver tissue	1.06E-04	-2.52E-01	-7.77E-01
Liver failure	DB99.7-DB99.8	Liver tissue	6.46E-02	-2.32E-01	-1.12E+00
Lung cancer	2C25	Lung tissue	8.26E-04	-7.44E-02	-2.64E-01
Lupus erythematosus	4A40	Whole blood	1.05E-03	-1.50E-01	-2.85E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	5.46E-01	-4.62E-02	-2.57E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.98E-01	3.21E-02	1.29E-01
Melanoma	2C30	Skin	7.36E-02	-3.54E-02	-7.92E-02
Multiple myeloma	2A83.1	Peripheral blood	5.70E-01	-3.20E-02	-1.44E-01
Multiple myeloma	2A83.1	Bone marrow	1.31E-04	-5.55E-01	-3.00E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.05E-01	2.13E-01	6.57E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.44E-01	-1.56E-02	-6.72E-02
Myelofibrosis	2A20.2	Whole blood	3.03E-02	7.87E-02	4.59E-01
Myocardial infarction	BA41-BA50	Peripheral blood	2.85E-02	1.88E-01	4.35E-01
Myopathy	8C70.6	Muscle tissue	2.97E-01	-3.85E-01	-4.16E-01
Neonatal sepsis	KA60	Whole blood	4.07E-01	-2.76E-02	-1.18E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.89E-04	-8.51E-01	-2.20E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	6.88E-01	-3.65E-03	-1.26E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	6.04E-01	1.19E-01	7.80E-01
Olive pollen allergy	CA08.00	Peripheral blood	7.84E-02	1.25E-01	6.58E-01
Oral cancer	2B6E	Oral tissue	2.02E-05	-1.14E+00	-7.54E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	1.91E-01	-5.18E-01	-4.91E-01
Osteoporosis	FB83.1	Bone marrow	3.94E-01	-1.18E-01	-4.53E-01
Ovarian cancer	2C73	Ovarian tissue	2.02E-01	-1.67E-02	-4.89E-02
Pancreatic cancer	2C10	Pancreas	1.53E-01	5.33E-02	1.28E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	9.49E-01	-2.49E-02	-1.35E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	5.79E-01	3.26E-02	1.73E-01
Pituitary cancer	2D12	Pituitary tissue	1.10E-02	1.76E-01	6.59E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.06E-01	1.68E-01	6.12E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	1.54E-02	8.73E-01	1.15E+00
Polycythemia vera	2A20.4	Whole blood	2.92E-06	8.30E-02	4.82E-01
Pompe disease	5C51.3	Biceps muscle	2.85E-09	3.54E+00	5.04E+00
Preterm birth	KA21.4Z	Myometrium	8.29E-01	3.41E-03	2.06E-02
Prostate cancer	2C82	Prostate	7.07E-02	-3.12E-01	-3.14E-01
Psoriasis	EA90	Skin	3.31E-02	-1.43E-01	-3.16E-01
Rectal cancer	2B92	Rectal colon tissue	4.68E-01	-1.05E-01	-4.95E-01
Renal cancer	2C90-2C91	Kidney	9.27E-03	-5.17E-01	-1.39E+00
Retinoblastoma	2D02.2	Uvea	4.37E-04	1.05E+00	9.04E+00
Rheumatoid arthritis	FA20	Synovial tissue	2.63E-02	-7.22E-01	-6.67E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	1.28E-01	-5.51E-02	-4.14E-01
Schizophrenia	6A20	Prefrontal cortex	7.60E-01	-2.02E-02	-5.23E-02
Schizophrenia	6A20	Superior temporal cortex	7.45E-01	2.02E-02	1.38E-01
Scleroderma	4A42.Z	Whole blood	8.63E-01	3.92E-02	3.77E-01
Seizure	8A60-8A6Z	Whole blood	9.59E-01	8.05E-03	3.65E-02
Sensitive skin	EK0Z	Skin	9.41E-01	-1.02E-01	-6.88E-01
Sepsis with septic shock	1G41	Whole blood	7.72E-03	-7.22E-02	-2.94E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	5.07E-01	-3.38E-02	-1.39E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	3.90E-01	1.16E-01	4.57E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	3.23E-01	6.00E-02	2.33E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	6.13E-01	1.21E-01	5.02E-01
Skin cancer	2C30-2C3Z	Skin	2.86E-01	-6.36E-02	-1.20E-01
Thrombocythemia	3B63	Whole blood	1.61E-02	1.04E-01	5.90E-01
Thrombocytopenia	3B64	Whole blood	9.55E-01	9.22E-02	2.22E-01
Thyroid cancer	2D10	Thyroid	7.89E-01	-1.91E-02	-7.92E-02
Tibial muscular dystrophy	8C75	Muscle tissue	8.03E-01	-1.24E-01	-1.14E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	6.87E-01	1.19E-01	6.58E-01
Type 2 diabetes	5A11	Liver tissue	1.64E-02	-2.18E-01	-1.88E+00
Ureter cancer	2C92	Urothelium	7.54E-01	-3.08E-02	-1.12E-01
Uterine cancer	2C78	Endometrium tissue	4.06E-02	1.30E-01	3.47E-01
Vitiligo	ED63.0	Skin	6.30E-04	-2.08E-01	-2.37E+00