Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEDMWFX)

• DME Name: Keto-steroid reductase (HSD17B7) DME Info
• Gene Name: HSD17B7

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.22E-01	2.55E-01	4.73E-01
Alopecia	ED70	Skin from scalp	1.57E-01	6.26E-02	2.33E-01
Alzheimer's disease	8A20	Entorhinal cortex	7.54E-09	3.28E-01	1.10E+00
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.41E-01	-3.95E-03	-2.71E-02
Aortic stenosis	BB70	Calcified aortic valve	8.44E-01	-1.81E-01	-1.69E-01
Apnea	7A40	Hyperplastic tonsil	3.48E-02	7.89E-01	3.11E+00
Arthropathy	FA00-FA5Z	Peripheral blood	4.62E-01	-1.01E-01	-7.98E-01
Asthma	CA23	Nasal and bronchial airway	9.87E-05	-2.14E-01	-5.70E-01
Atopic dermatitis	EA80	Skin	2.87E-07	2.60E-01	1.48E+00
Autism	6A02	Whole blood	4.19E-01	5.17E-02	2.21E-01
Autoimmune uveitis	9A96	Peripheral monocyte	1.03E-01	5.54E-01	2.76E+00
Autosomal dominant monocytopenia	4B04	Whole blood	6.25E-01	-3.56E-03	-1.44E-02
Bacterial infection of gingival	1C1H	Gingival tissue	4.64E-05	-1.46E-01	-6.13E-01
Batten disease	5C56.1	Whole blood	2.56E-01	-1.57E-01	-8.47E-01
Behcet's disease	4A62	Peripheral blood	5.94E-01	9.86E-03	4.09E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.72E-02	1.38E-01	7.92E-01
Bladder cancer	2C94	Bladder tissue	5.75E-02	-4.38E-01	-1.37E+00
Breast cancer	2C60-2C6Z	Breast tissue	7.07E-83	8.68E-01	1.94E+00
Cardioembolic stroke	8B11.20	Whole blood	4.62E-06	-3.55E-01	-1.31E+00
Cervical cancer	2C77	Cervical tissue	8.32E-01	-4.47E-03	-9.04E-03
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	2.06E-01	-7.34E-02	-3.05E-01
Chronic hepatitis C	1E51.1	Whole blood	1.50E-01	1.61E-01	8.30E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	6.02E-01	9.22E-02	2.81E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	8.88E-01	-1.88E-02	-6.39E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	2.26E-01	-1.87E-01	-8.85E-01
Colon cancer	2B90	Colon tissue	2.22E-40	6.06E-01	1.56E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	9.23E-01	-5.12E-03	-6.90E-03
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	8.17E-01	1.70E-02	6.72E-02
Endometriosis	GA10	Endometrium tissue	6.04E-01	-4.09E-02	-9.49E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.55E-02	9.63E-02	4.73E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.53E-04	4.00E-01	1.42E+00
Gastric cancer	2B72	Gastric tissue	8.45E-01	8.81E-02	2.60E-01
Glioblastopma	2A00.00	Nervous tissue	7.15E-02	1.83E-02	3.28E-02
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	2.66E-04	-7.91E-01	-8.72E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	3.76E-01	-2.91E-01	-3.62E-01
Head and neck cancer	2D42	Head and neck tissue	4.53E-16	-3.58E-01	-1.54E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.68E-01	2.71E-01	4.40E-01
Huntington's disease	8A01.10	Whole blood	6.07E-01	-9.14E-02	-3.03E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	4.77E-02	-3.58E-01	-1.05E+00
Immunodeficiency	4A00-4A20	Peripheral blood	5.37E-03	-1.84E-01	-1.23E+00
Influenza	1E30	Whole blood	1.79E-01	-1.14E-01	-4.11E-01
Interstitial cystitis	GC00.3	Bladder tissue	7.35E-01	5.81E-02	8.95E-01
Intracranial aneurysm	8B01.0	Intracranial artery	2.72E-01	7.74E-02	2.17E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.12E-01	1.34E-01	3.56E-01
Ischemic stroke	8B11	Peripheral blood	6.83E-02	-7.23E-02	-2.29E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.56E-03	-7.59E-02	-2.19E-01
Lateral sclerosis	8B60.4	Skin	2.68E-01	2.49E-01	7.19E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	1.73E-01	5.39E-01	7.70E-01
Liver cancer	2C12.0	Liver tissue	4.24E-07	6.20E-01	1.08E+00
Liver failure	DB99.7-DB99.8	Liver tissue	2.00E-01	-6.16E-02	-8.47E-02
Lung cancer	2C25	Lung tissue	3.18E-05	2.13E-01	4.25E-01
Lupus erythematosus	4A40	Whole blood	7.37E-04	9.49E-02	2.41E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	6.14E-01	2.25E-02	1.27E-01
Major depressive disorder	6A70-6A7Z	Whole blood	6.09E-01	-2.86E-02	-6.31E-02
Melanoma	2C30	Skin	8.63E-03	-5.51E-01	-7.85E-01
Multiple myeloma	2A83.1	Peripheral blood	9.94E-02	-1.14E-01	-3.78E-01
Multiple myeloma	2A83.1	Bone marrow	9.79E-05	6.40E-01	2.76E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.13E-01	-1.66E-01	-4.75E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	7.77E-01	6.72E-02	2.10E-01
Myelofibrosis	2A20.2	Whole blood	2.70E-02	-2.33E-01	-1.29E+00
Myocardial infarction	BA41-BA50	Peripheral blood	1.40E-02	-2.79E-01	-4.67E-01
Myopathy	8C70.6	Muscle tissue	4.31E-01	-7.61E-02	-1.97E-01
Neonatal sepsis	KA60	Whole blood	3.25E-06	-2.61E-01	-6.11E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.64E-07	-1.21E+00	-3.99E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.35E-01	4.93E-01	1.70E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.64E-01	-4.90E-01	-9.28E-01
Olive pollen allergy	CA08.00	Peripheral blood	6.38E-02	-2.14E-01	-1.09E+00
Oral cancer	2B6E	Oral tissue	3.55E-01	1.86E-01	2.82E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	8.69E-01	-3.13E-02	-8.41E-02
Osteoporosis	FB83.1	Bone marrow	7.70E-02	-4.09E-01	-1.04E+00
Ovarian cancer	2C73	Ovarian tissue	1.93E-01	1.84E-02	2.71E-02
Pancreatic cancer	2C10	Pancreas	1.23E-01	6.02E-01	7.60E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	1.24E-01	6.02E-02	1.98E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.10E-02	-8.55E-02	-4.59E-01
Pituitary cancer	2D12	Pituitary tissue	6.61E-05	-5.52E-01	-2.22E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.67E-03	-6.55E-01	-2.31E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	3.00E-01	-6.37E-02	-3.95E-01
Polycythemia vera	2A20.4	Whole blood	3.06E-09	-3.27E-01	-1.41E+00
Pompe disease	5C51.3	Biceps muscle	2.95E-01	1.07E-01	4.16E-01
Preterm birth	KA21.4Z	Myometrium	7.45E-02	-3.39E-01	-8.19E-01
Prostate cancer	2C82	Prostate	1.07E-04	-5.72E-01	-1.18E+00
Psoriasis	EA90	Skin	7.08E-01	1.32E-01	3.31E-01
Rectal cancer	2B92	Rectal colon tissue	3.20E-04	8.52E-01	3.29E+00
Renal cancer	2C90-2C91	Kidney	5.48E-04	6.04E-01	1.60E+00
Retinoblastoma	2D02.2	Uvea	2.82E-02	2.81E-01	1.15E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.16E-02	3.56E-01	1.15E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	1.91E-01	-4.02E-02	-2.51E-01
Schizophrenia	6A20	Prefrontal cortex	6.69E-02	5.75E-02	1.73E-01
Schizophrenia	6A20	Superior temporal cortex	4.76E-01	6.47E-02	2.74E-01
Scleroderma	4A42.Z	Whole blood	1.42E-03	-1.60E-01	-1.29E+00
Seizure	8A60-8A6Z	Whole blood	3.51E-01	2.16E-02	8.65E-02
Sensitive skin	EK0Z	Skin	9.23E-01	-1.15E-02	-8.86E-02
Sepsis with septic shock	1G41	Whole blood	1.04E-06	-1.26E-01	-3.01E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	7.44E-02	-3.48E-01	-1.23E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	9.46E-02	-4.20E-01	-7.67E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	1.55E-02	-2.73E-01	-1.77E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.83E-01	-2.07E-02	-6.00E-02
Skin cancer	2C30-2C3Z	Skin	4.35E-01	7.18E-02	1.66E-01
Thrombocythemia	3B63	Whole blood	4.63E-02	-3.00E-01	-1.54E+00
Thrombocytopenia	3B64	Whole blood	8.91E-01	-1.72E-05	-4.38E-05
Thyroid cancer	2D10	Thyroid	2.33E-05	1.65E-01	4.94E-01
Tibial muscular dystrophy	8C75	Muscle tissue	4.34E-02	1.79E-01	6.39E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	6.00E-02	2.95E-01	1.55E+00
Type 2 diabetes	5A11	Liver tissue	1.21E-01	3.10E-01	1.30E+00
Ureter cancer	2C92	Urothelium	3.96E-01	9.04E-02	4.29E-01
Uterine cancer	2C78	Endometrium tissue	3.38E-04	2.09E-01	4.99E-01
Vitiligo	ED63.0	Skin	6.23E-01	-4.63E-02	-2.27E-01