Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEH0J8X)

• DME Name: Arachidonate 15-lipoxygenase (ALOX15) DME Info
• Gene Name: ALOX15

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	8.36E-09	-1.60E-01	-5.39E-01
Alopecia	ED70	Skin from scalp	3.32E-06	3.59E-01	8.37E-01
Alzheimer's disease	8A20	Entorhinal cortex	4.61E-01	-2.18E-02	-1.44E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	6.59E-02	4.55E-02	4.76E-01
Aortic stenosis	BB70	Calcified aortic valve	7.78E-02	-1.01E-01	-4.34E-01
Apnea	7A40	Hyperplastic tonsil	5.83E-01	-2.59E-02	-2.28E-01
Arthropathy	FA00-FA5Z	Peripheral blood	6.02E-01	2.28E-01	4.09E-01
Asthma	CA23	Nasal and bronchial airway	3.86E-02	2.25E-01	4.01E-01
Atopic dermatitis	EA80	Skin	1.27E-03	2.80E-01	1.38E+00
Autism	6A02	Whole blood	9.44E-01	-1.19E-01	-2.85E-01
Autoimmune uveitis	9A96	Peripheral monocyte	7.51E-02	-5.17E-02	-3.96E-01
Autosomal dominant monocytopenia	4B04	Whole blood	6.66E-01	-1.30E-01	-1.18E-01
Bacterial infection of gingival	1C1H	Gingival tissue	8.42E-02	1.54E-02	1.36E-01
Batten disease	5C56.1	Whole blood	5.09E-01	-3.48E-02	-5.39E-01
Behcet's disease	4A62	Peripheral blood	2.24E-01	-9.27E-02	-4.76E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.82E-01	-3.86E-02	-2.01E-01
Bladder cancer	2C94	Bladder tissue	1.69E-01	4.09E-02	2.75E-01
Breast cancer	2C60-2C6Z	Breast tissue	4.05E-01	-1.46E-02	-6.94E-02
Cardioembolic stroke	8B11.20	Whole blood	1.95E-05	-1.38E+00	-1.44E+00
Cervical cancer	2C77	Cervical tissue	3.94E-01	-5.99E-02	-3.29E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.64E-01	3.38E-02	2.04E-02
Chronic hepatitis C	1E51.1	Whole blood	6.96E-01	-2.23E-03	-2.47E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.54E-01	-5.26E-02	-1.39E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.66E-03	-3.11E-01	-5.13E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	7.12E-02	-1.18E+00	-9.40E-01
Colon cancer	2B90	Colon tissue	1.21E-06	-1.76E-01	-5.88E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	8.35E-01	8.43E-02	3.16E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.19E-01	8.44E-02	9.75E-01
Endometriosis	GA10	Endometrium tissue	8.52E-01	-1.97E-02	-1.21E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.56E-01	-4.18E-02	-4.50E-01
Familial hypercholesterolemia	5C80.00	Whole blood	7.89E-05	-3.61E-01	-9.12E-01
Gastric cancer	2B72	Gastric tissue	3.82E-01	-2.75E-01	-7.54E-01
Glioblastopma	2A00.00	Nervous tissue	3.47E-56	-2.30E-01	-1.00E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	4.93E-01	1.30E-01	7.60E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.38E-01	2.54E-03	1.89E-02
Head and neck cancer	2D42	Head and neck tissue	3.00E-12	-2.62E-01	-8.95E-02
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	2.49E-01	-6.99E-02	-2.30E-01
Huntington's disease	8A01.10	Whole blood	2.91E-01	-3.37E-02	-1.62E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	3.40E-03	7.97E-01	3.17E+00
Immunodeficiency	4A00-4A20	Peripheral blood	6.08E-01	-5.41E-02	-6.21E-01
Influenza	1E30	Whole blood	7.76E-03	5.39E-01	5.14E+00
Interstitial cystitis	GC00.3	Bladder tissue	4.46E-01	4.94E-02	2.82E-01
Intracranial aneurysm	8B01.0	Intracranial artery	6.51E-01	-3.58E-02	-1.83E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	5.29E-01	2.54E-02	1.18E-01
Ischemic stroke	8B11	Peripheral blood	9.25E-01	-5.90E-02	-4.13E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.77E-03	7.62E-02	5.21E-02
Lateral sclerosis	8B60.4	Skin	1.60E-01	-6.52E-02	-6.59E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	9.03E-02	4.80E-01	1.49E+00
Liver cancer	2C12.0	Liver tissue	6.34E-03	-1.05E-01	-5.20E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.74E-02	-2.42E-01	-1.01E+00
Lung cancer	2C25	Lung tissue	1.84E-06	-2.96E-01	-3.53E-01
Lupus erythematosus	4A40	Whole blood	3.09E-01	-1.71E-01	-2.01E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	5.77E-01	-5.28E-02	-3.38E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.60E-01	2.55E-01	2.20E-01
Melanoma	2C30	Skin	1.37E-02	-3.04E-01	-8.75E-01
Multiple myeloma	2A83.1	Peripheral blood	7.95E-01	7.76E-03	7.12E-02
Multiple myeloma	2A83.1	Bone marrow	2.05E-01	-1.74E-02	-1.71E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.00E-01	-1.35E-01	-4.57E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	3.39E-01	9.39E-03	9.45E-02
Myelofibrosis	2A20.2	Whole blood	5.16E-02	2.45E-01	4.87E-01
Myocardial infarction	BA41-BA50	Peripheral blood	2.36E-01	9.30E-02	2.16E-01
Myopathy	8C70.6	Muscle tissue	2.23E-01	-6.83E-02	-2.05E-01
Neonatal sepsis	KA60	Whole blood	1.01E-08	-2.21E-01	-5.67E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	3.72E-03	-2.73E-01	-1.20E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	3.17E-01	-4.65E-02	-7.38E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	6.10E-04	-1.21E+00	-2.96E+00
Olive pollen allergy	CA08.00	Peripheral blood	6.23E-01	-8.05E-03	-3.61E-02
Oral cancer	2B6E	Oral tissue	2.11E-03	-1.92E-01	-6.35E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.74E-01	-1.03E-01	-6.04E-01
Osteoporosis	FB83.1	Bone marrow	9.50E-01	4.18E-02	2.36E-01
Ovarian cancer	2C73	Ovarian tissue	5.78E-01	-2.43E-02	-2.12E-01
Pancreatic cancer	2C10	Pancreas	2.39E-02	-1.84E-01	-8.18E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	7.49E-01	2.39E-03	1.23E-02
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	4.87E-01	-5.77E-02	-3.30E-01
Pituitary cancer	2D12	Pituitary tissue	9.73E-01	-7.72E-02	-3.19E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	9.70E-01	3.54E-03	2.42E-02
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	8.08E-01	4.80E-04	3.26E-03
Polycythemia vera	2A20.4	Whole blood	2.72E-01	1.78E-01	3.50E-01
Pompe disease	5C51.3	Biceps muscle	1.38E-01	-1.61E-02	-7.16E-02
Preterm birth	KA21.4Z	Myometrium	1.76E-01	-1.36E-01	-1.15E+00
Prostate cancer	2C82	Prostate	3.91E-03	7.71E-02	1.38E-01
Psoriasis	EA90	Skin	8.84E-01	-1.80E-03	-5.66E-03
Rectal cancer	2B92	Rectal colon tissue	6.24E-01	-1.38E-01	-6.26E-01
Renal cancer	2C90-2C91	Kidney	7.81E-03	-2.27E-01	-5.32E-01
Retinoblastoma	2D02.2	Uvea	2.38E-01	-1.42E-01	-2.14E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.23E-02	-6.43E-01	-1.57E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	8.22E-01	8.69E-02	3.59E-01
Schizophrenia	6A20	Prefrontal cortex	3.14E-01	-2.17E-02	-1.08E-01
Schizophrenia	6A20	Superior temporal cortex	4.93E-01	-3.90E-03	-3.63E-02
Scleroderma	4A42.Z	Whole blood	3.11E-01	1.10E-01	3.35E-01
Seizure	8A60-8A6Z	Whole blood	9.65E-01	2.12E-01	4.25E-01
Sensitive skin	EK0Z	Skin	6.90E-01	-2.02E-01	-5.34E-01
Sepsis with septic shock	1G41	Whole blood	2.01E-20	-2.34E-01	-6.23E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.39E-01	-1.09E-01	-9.77E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	7.08E-01	8.83E-02	2.05E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.17E-01	2.10E-02	1.35E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.16E-01	-9.59E-03	-1.69E-01
Skin cancer	2C30-2C3Z	Skin	4.06E-08	-1.52E-01	-3.72E-01
Thrombocythemia	3B63	Whole blood	1.98E-01	8.27E-02	1.73E-01
Thrombocytopenia	3B64	Whole blood	3.89E-01	4.96E-02	3.08E-01
Thyroid cancer	2D10	Thyroid	8.69E-02	4.18E-02	2.16E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.96E-02	-2.25E-01	-7.52E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.48E-01	1.14E-01	1.64E+00
Type 2 diabetes	5A11	Liver tissue	6.68E-01	-3.08E-02	-5.48E-01
Ureter cancer	2C92	Urothelium	7.70E-01	7.90E-02	2.85E-01
Uterine cancer	2C78	Endometrium tissue	7.10E-03	-1.20E-04	-4.71E-04
Vitiligo	ED63.0	Skin	3.00E-01	3.69E-01	9.12E-01