Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEMPH4I)

• DME Name: Uridine/cytidine monophosphate kinase (UMPK) DME Info
• Gene Name: CMPK1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	7.90E-20	3.39E-01	8.49E-01
Alopecia	ED70	Skin from scalp	8.58E-01	-6.86E-03	-2.00E-02
Alzheimer's disease	8A20	Entorhinal cortex	1.66E-01	3.10E-02	1.09E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.40E-01	-1.39E-02	-9.73E-02
Aortic stenosis	BB70	Calcified aortic valve	9.60E-01	-2.55E-01	-1.82E-01
Apnea	7A40	Hyperplastic tonsil	3.26E-01	2.66E-01	4.38E-01
Arthropathy	FA00-FA5Z	Peripheral blood	1.32E-01	-2.56E-01	-7.07E-01
Asthma	CA23	Nasal and bronchial airway	6.64E-09	3.47E-01	7.28E-01
Atopic dermatitis	EA80	Skin	6.45E-07	-5.27E-01	-2.30E+00
Autism	6A02	Whole blood	4.14E-01	3.65E-01	6.16E-01
Autoimmune uveitis	9A96	Peripheral monocyte	1.39E-01	-3.88E-01	-9.72E-01
Autosomal dominant monocytopenia	4B04	Whole blood	6.18E-01	-3.50E-02	-7.26E-02
Bacterial infection of gingival	1C1H	Gingival tissue	1.15E-02	-1.22E-01	-4.48E-01
Batten disease	5C56.1	Whole blood	2.18E-02	-3.16E-01	-1.75E+00
Behcet's disease	4A62	Peripheral blood	8.58E-01	3.66E-02	1.70E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.58E-01	-5.25E-02	-2.55E-01
Bladder cancer	2C94	Bladder tissue	6.67E-06	-4.98E-01	-2.81E+00
Breast cancer	2C60-2C6Z	Breast tissue	3.08E-06	-3.18E-01	-4.94E-01
Cardioembolic stroke	8B11.20	Whole blood	3.60E-01	-8.95E-02	-3.37E-01
Cervical cancer	2C77	Cervical tissue	2.38E-01	5.88E-02	1.48E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.43E-01	-8.52E-02	-6.87E-02
Chronic hepatitis C	1E51.1	Whole blood	1.45E-01	-5.07E-02	-2.44E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.13E-01	-2.82E-01	-6.68E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	3.18E-03	-1.53E-01	-4.61E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	3.83E-01	8.46E-02	2.23E-01
Colon cancer	2B90	Colon tissue	1.13E-17	-2.16E-01	-7.23E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.28E-01	-1.54E-01	-1.87E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	2.87E-01	1.20E-02	1.60E-02
Endometriosis	GA10	Endometrium tissue	5.58E-01	-6.34E-02	-9.55E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	5.36E-02	1.02E-01	8.40E-01
Familial hypercholesterolemia	5C80.00	Whole blood	5.97E-05	6.90E-01	1.29E+00
Gastric cancer	2B72	Gastric tissue	3.37E-02	7.33E-01	3.36E+00
Glioblastopma	2A00.00	Nervous tissue	6.10E-16	2.80E-01	5.79E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	7.44E-01	-7.70E-02	-2.77E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	4.96E-01	-1.68E-01	-3.00E-01
Head and neck cancer	2D42	Head and neck tissue	7.74E-12	-3.05E-01	-8.52E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	6.74E-01	4.73E-02	9.20E-02
Huntington's disease	8A01.10	Whole blood	6.20E-01	-6.51E-02	-1.36E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.01E-01	-3.90E-02	-1.59E-01
Immunodeficiency	4A00-4A20	Peripheral blood	7.95E-02	-2.03E-01	-8.97E-01
Influenza	1E30	Whole blood	3.58E-01	-2.65E-01	-1.12E+00
Interstitial cystitis	GC00.3	Bladder tissue	8.47E-01	3.01E-02	3.11E-01
Intracranial aneurysm	8B01.0	Intracranial artery	5.28E-01	-1.56E-01	-2.60E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	4.59E-01	5.25E-02	2.82E-01
Ischemic stroke	8B11	Peripheral blood	1.78E-01	6.37E-02	2.33E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	9.19E-01	-4.15E-02	-8.87E-02
Lateral sclerosis	8B60.4	Skin	4.41E-01	-6.77E-02	-6.13E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	6.77E-01	-3.59E-03	-4.17E-03
Liver cancer	2C12.0	Liver tissue	1.55E-02	-8.05E-02	-1.40E-01
Liver failure	DB99.7-DB99.8	Liver tissue	5.28E-06	-9.75E-01	-3.20E+00
Lung cancer	2C25	Lung tissue	4.01E-10	2.26E-01	6.43E-01
Lupus erythematosus	4A40	Whole blood	4.76E-01	4.51E-02	6.46E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	6.73E-01	-4.92E-03	-2.57E-02
Major depressive disorder	6A70-6A7Z	Whole blood	3.66E-01	6.22E-02	1.65E-01
Melanoma	2C30	Skin	1.24E-02	-1.98E-01	-5.34E-01
Multiple myeloma	2A83.1	Peripheral blood	5.34E-01	9.22E-02	6.29E-01
Multiple myeloma	2A83.1	Bone marrow	3.35E-06	1.09E+00	4.16E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.84E-01	-1.73E-01	-7.38E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.71E-01	6.83E-03	2.18E-02
Myelofibrosis	2A20.2	Whole blood	3.10E-02	-2.75E-01	-7.32E-01
Myocardial infarction	BA41-BA50	Peripheral blood	5.15E-02	-2.00E-01	-3.35E-01
Myopathy	8C70.6	Muscle tissue	8.26E-01	5.99E-02	3.26E-01
Neonatal sepsis	KA60	Whole blood	8.38E-04	-3.95E-01	-6.52E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	5.94E-03	6.37E-01	9.79E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	9.68E-01	5.45E-02	1.31E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	4.35E-02	-3.23E-01	-1.46E+00
Olive pollen allergy	CA08.00	Peripheral blood	6.08E-01	4.00E-02	1.29E-01
Oral cancer	2B6E	Oral tissue	6.62E-01	1.07E-01	1.92E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	9.81E-02	2.09E-01	5.39E-01
Osteoporosis	FB83.1	Bone marrow	5.13E-01	4.86E-02	1.57E-01
Ovarian cancer	2C73	Ovarian tissue	5.39E-03	6.57E-01	1.35E+00
Pancreatic cancer	2C10	Pancreas	2.73E-04	5.37E-01	1.41E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	9.09E-01	-3.68E-02	-1.22E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	6.98E-05	-2.69E-01	-1.32E+00
Pituitary cancer	2D12	Pituitary tissue	2.39E-01	-1.21E-01	-4.59E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.23E-01	-1.09E-01	-3.75E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.98E-02	1.08E-01	3.07E-01
Polycythemia vera	2A20.4	Whole blood	9.21E-07	-3.99E-01	-1.01E+00
Pompe disease	5C51.3	Biceps muscle	6.08E-01	-5.54E-04	-4.13E-03
Preterm birth	KA21.4Z	Myometrium	1.70E-01	3.46E-01	5.67E-01
Prostate cancer	2C82	Prostate	5.43E-01	1.37E-01	4.18E-01
Psoriasis	EA90	Skin	4.49E-01	-3.63E-02	-1.32E-01
Rectal cancer	2B92	Rectal colon tissue	3.29E-02	-2.12E-01	-9.35E-01
Renal cancer	2C90-2C91	Kidney	4.33E-04	8.00E-01	1.78E+00
Retinoblastoma	2D02.2	Uvea	4.71E-03	4.82E-01	1.41E+00
Rheumatoid arthritis	FA20	Synovial tissue	2.50E-02	3.13E-01	1.31E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.77E-01	-7.77E-02	-2.92E-01
Schizophrenia	6A20	Prefrontal cortex	9.82E-01	-7.64E-02	-1.21E-01
Schizophrenia	6A20	Superior temporal cortex	3.97E-01	-1.15E-01	-4.25E-01
Scleroderma	4A42.Z	Whole blood	3.53E-02	-2.21E-01	-1.24E+00
Seizure	8A60-8A6Z	Whole blood	4.46E-01	5.06E-01	1.21E+00
Sensitive skin	EK0Z	Skin	8.61E-01	1.12E-01	3.62E-01
Sepsis with septic shock	1G41	Whole blood	1.06E-44	-7.26E-01	-1.43E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.29E-01	-3.21E-01	-7.31E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.00E-02	4.59E-01	1.19E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.48E-01	-9.54E-02	-1.32E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.63E-01	-1.58E-01	-1.18E+00
Skin cancer	2C30-2C3Z	Skin	5.21E-42	-4.89E-01	-1.65E+00
Thrombocythemia	3B63	Whole blood	3.27E-03	-1.91E-01	-5.04E-01
Thrombocytopenia	3B64	Whole blood	5.33E-01	-4.72E-01	-5.34E-01
Thyroid cancer	2D10	Thyroid	9.45E-04	-1.39E-01	-4.83E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.00E+00	-7.66E-02	-3.43E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.31E-01	-2.91E-01	-9.42E-01
Type 2 diabetes	5A11	Liver tissue	6.53E-02	5.91E-01	1.69E+00
Ureter cancer	2C92	Urothelium	9.70E-01	1.52E-01	1.88E-01
Uterine cancer	2C78	Endometrium tissue	2.61E-03	2.57E-01	4.22E-01
Vitiligo	ED63.0	Skin	6.81E-02	-1.03E-01	-8.19E-01