Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DESWQMH)

• DME Name: Propionyl-CoA carboxylase beta (PCCB) DME Info
• Gene Name: PCCB

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.83E-03	-4.27E-02	-1.32E-01
Alopecia	ED70	Skin from scalp	8.21E-01	-3.59E-02	-1.27E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.47E-02	-1.76E-02	-9.60E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.54E-02	1.38E-01	5.95E-01
Aortic stenosis	BB70	Calcified aortic valve	5.13E-01	2.05E-01	3.55E-01
Apnea	7A40	Hyperplastic tonsil	6.19E-01	-5.56E-02	-1.55E-01
Arthropathy	FA00-FA5Z	Peripheral blood	3.84E-01	-6.67E-02	-5.44E-01
Asthma	CA23	Nasal and bronchial airway	3.58E-06	2.31E-01	3.58E-01
Atopic dermatitis	EA80	Skin	7.70E-02	8.77E-02	7.23E-01
Autism	6A02	Whole blood	4.59E-02	-2.29E-02	-9.82E-02
Autoimmune uveitis	9A96	Peripheral monocyte	2.12E-01	-2.14E-01	-1.97E+00
Autosomal dominant monocytopenia	4B04	Whole blood	2.77E-01	-2.24E-02	-1.46E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.90E-01	9.87E-03	5.39E-02
Batten disease	5C56.1	Whole blood	3.52E-01	-7.28E-02	-5.33E-01
Behcet's disease	4A62	Peripheral blood	8.82E-01	7.08E-02	3.55E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.88E-01	-1.55E-02	-1.37E-01
Bladder cancer	2C94	Bladder tissue	2.19E-02	-2.65E-01	-1.72E+00
Breast cancer	2C60-2C6Z	Breast tissue	6.15E-16	2.28E-01	5.98E-01
Cardioembolic stroke	8B11.20	Whole blood	9.32E-01	-8.11E-02	-5.01E-01
Cervical cancer	2C77	Cervical tissue	3.23E-01	-2.44E-03	-8.97E-03
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	5.12E-01	1.98E-02	4.69E-02
Chronic hepatitis C	1E51.1	Whole blood	3.55E-01	-3.62E-02	-3.02E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	8.36E-01	5.88E-02	2.99E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.74E-02	-5.12E-02	-2.72E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	8.09E-01	-4.16E-02	-3.40E-01
Colon cancer	2B90	Colon tissue	1.20E-14	-1.90E-01	-8.67E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.45E-01	-3.63E-01	-1.59E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	1.17E-01	4.92E-02	1.34E-01
Endometriosis	GA10	Endometrium tissue	7.04E-02	-1.18E-01	-4.19E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	2.37E-01	-1.15E-01	-6.66E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.89E-01	9.19E-02	5.08E-01
Gastric cancer	2B72	Gastric tissue	3.28E-01	1.74E-01	4.22E-01
Glioblastopma	2A00.00	Nervous tissue	5.66E-32	1.98E-01	8.22E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	9.63E-02	3.88E-01	2.73E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	6.73E-02	2.79E-01	6.94E-01
Head and neck cancer	2D42	Head and neck tissue	4.68E-05	-1.41E-01	-8.47E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	7.28E-01	2.24E-02	8.03E-02
Huntington's disease	8A01.10	Whole blood	7.47E-02	-2.21E-01	-9.73E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.07E-02	-1.68E-01	-1.50E+00
Immunodeficiency	4A00-4A20	Peripheral blood	8.17E-01	-5.56E-02	-3.91E-01
Influenza	1E30	Whole blood	3.90E-01	-2.34E-01	-1.25E+00
Interstitial cystitis	GC00.3	Bladder tissue	6.64E-01	-3.64E-02	-3.20E-01
Intracranial aneurysm	8B01.0	Intracranial artery	1.47E-01	2.90E-01	9.83E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.37E-01	-2.77E-02	-9.62E-02
Ischemic stroke	8B11	Peripheral blood	8.99E-04	-1.69E-01	-1.69E+00
Juvenile idiopathic arthritis	FA24	Peripheral blood	2.20E-04	-1.46E-01	-6.53E-01
Lateral sclerosis	8B60.4	Skin	1.62E-02	2.44E-01	2.37E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	4.43E-01	-7.58E-02	-2.13E-01
Liver cancer	2C12.0	Liver tissue	6.99E-17	-4.85E-01	-1.87E+00
Liver failure	DB99.7-DB99.8	Liver tissue	1.52E-03	-7.32E-01	-2.29E+00
Lung cancer	2C25	Lung tissue	1.93E-50	2.83E-01	1.44E+00
Lupus erythematosus	4A40	Whole blood	2.41E-02	1.76E-01	3.67E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	4.66E-01	-2.56E-02	-2.51E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.18E-01	-6.93E-02	-2.90E-01
Melanoma	2C30	Skin	4.73E-02	-5.93E-01	-6.23E-01
Multiple myeloma	2A83.1	Peripheral blood	8.86E-01	-3.42E-02	-1.38E-01
Multiple myeloma	2A83.1	Bone marrow	1.69E-05	5.20E-01	3.40E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.33E-01	-9.12E-02	-3.12E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	4.04E-01	-2.24E-03	-1.04E-02
Myelofibrosis	2A20.2	Whole blood	5.35E-01	-1.38E-01	-1.15E+00
Myocardial infarction	BA41-BA50	Peripheral blood	1.00E-01	-3.90E-01	-5.21E-01
Myopathy	8C70.6	Muscle tissue	7.26E-01	1.48E-02	7.88E-02
Neonatal sepsis	KA60	Whole blood	3.81E-08	-2.05E-01	-8.28E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	6.20E-05	4.02E-01	2.07E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	7.16E-01	-9.07E-02	-3.90E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	4.57E-01	2.99E-02	1.91E-01
Olive pollen allergy	CA08.00	Peripheral blood	6.70E-02	1.36E-01	1.02E+00
Oral cancer	2B6E	Oral tissue	1.61E-05	2.29E-01	9.91E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	8.22E-01	-1.53E-01	-4.46E-01
Osteoporosis	FB83.1	Bone marrow	2.80E-02	3.13E-01	2.01E+00
Ovarian cancer	2C73	Ovarian tissue	7.94E-07	7.40E-01	3.97E+00
Pancreatic cancer	2C10	Pancreas	1.32E-03	-2.43E-01	-1.07E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	2.86E-01	-6.33E-02	-3.07E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	9.09E-01	3.83E-02	3.62E-01
Pituitary cancer	2D12	Pituitary tissue	1.03E-04	3.57E-01	1.87E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	9.86E-07	8.20E-01	4.07E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.72E-01	-3.35E-02	-2.85E-01
Polycythemia vera	2A20.4	Whole blood	2.69E-12	-1.78E-01	-1.45E+00
Pompe disease	5C51.3	Biceps muscle	4.32E-03	3.95E-01	1.76E+00
Preterm birth	KA21.4Z	Myometrium	8.04E-01	3.22E-02	4.67E-01
Prostate cancer	2C82	Prostate	2.13E-10	6.62E-01	2.23E+00
Psoriasis	EA90	Skin	1.63E-11	2.15E-01	6.24E-01
Rectal cancer	2B92	Rectal colon tissue	2.39E-01	-1.17E-01	-7.82E-01
Renal cancer	2C90-2C91	Kidney	3.45E-04	-3.88E-01	-1.65E+00
Retinoblastoma	2D02.2	Uvea	3.08E-05	4.94E-01	3.15E+00
Rheumatoid arthritis	FA20	Synovial tissue	3.58E-01	-2.51E-01	-6.78E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.08E-01	2.95E-02	2.11E-01
Schizophrenia	6A20	Prefrontal cortex	3.19E-02	-2.03E-02	-1.58E-01
Schizophrenia	6A20	Superior temporal cortex	2.10E-01	-2.15E-02	-1.60E-01
Scleroderma	4A42.Z	Whole blood	2.04E-01	9.53E-02	7.50E-01
Seizure	8A60-8A6Z	Whole blood	8.81E-01	1.62E-01	6.56E-01
Sensitive skin	EK0Z	Skin	7.60E-01	5.12E-03	2.55E-02
Sepsis with septic shock	1G41	Whole blood	1.79E-02	-6.77E-02	-2.62E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.56E-01	-1.44E-01	-1.01E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	6.02E-02	-2.78E-01	-1.10E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	6.43E-01	-1.36E-02	-9.24E-02
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.11E-01	-9.10E-02	-2.26E-01
Skin cancer	2C30-2C3Z	Skin	1.80E-08	2.97E-01	5.39E-01
Thrombocythemia	3B63	Whole blood	1.04E-06	-1.66E-01	-1.42E+00
Thrombocytopenia	3B64	Whole blood	3.72E-01	-2.20E-01	-5.14E-01
Thyroid cancer	2D10	Thyroid	6.88E-01	-1.63E-02	-7.81E-02
Tibial muscular dystrophy	8C75	Muscle tissue	4.92E-01	3.44E-03	2.19E-02
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	8.59E-01	4.12E-02	6.12E-01
Type 2 diabetes	5A11	Liver tissue	6.58E-01	9.58E-03	4.87E-02
Ureter cancer	2C92	Urothelium	4.76E-01	2.11E-02	5.25E-02
Uterine cancer	2C78	Endometrium tissue	5.44E-03	1.10E-01	3.22E-01
Vitiligo	ED63.0	Skin	3.92E-01	1.28E-01	4.88E-01