Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEZT8FM)

• DME Name: Retinoic acid 4-hydroxylase 26B1 (CYP26B1) DME Info
• Gene Name: CYP26B1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.88E-03	2.23E-02	1.18E-01
Alopecia	ED70	Skin from scalp	1.64E-01	-5.59E-03	-3.75E-02
Alzheimer's disease	8A20	Entorhinal cortex	2.39E-11	-5.88E-01	-8.76E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.13E-01	7.27E-02	6.58E-01
Aortic stenosis	BB70	Calcified aortic valve	1.61E-01	-2.79E-01	-8.05E-01
Apnea	7A40	Hyperplastic tonsil	1.28E-02	-7.45E-01	-1.99E+00
Arthropathy	FA00-FA5Z	Peripheral blood	3.97E-02	1.36E-01	6.51E-01
Asthma	CA23	Nasal and bronchial airway	1.12E-02	-2.20E-01	-5.88E-01
Atopic dermatitis	EA80	Skin	1.52E-07	-3.13E-01	-1.47E+00
Autism	6A02	Whole blood	6.58E-01	6.68E-03	3.34E-02
Autoimmune uveitis	9A96	Peripheral monocyte	4.88E-02	-3.06E-01	-3.14E+00
Autosomal dominant monocytopenia	4B04	Whole blood	2.00E-01	1.20E-01	2.80E-01
Bacterial infection of gingival	1C1H	Gingival tissue	9.47E-04	-2.23E-01	-6.25E-01
Batten disease	5C56.1	Whole blood	1.16E-01	1.15E-01	9.07E-01
Behcet's disease	4A62	Peripheral blood	1.41E-01	9.53E-02	4.32E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.73E-01	-1.32E-01	-2.91E-01
Bladder cancer	2C94	Bladder tissue	2.35E-01	-2.23E-01	-7.87E-01
Breast cancer	2C60-2C6Z	Breast tissue	5.55E-47	-8.56E-01	-1.37E+00
Cardioembolic stroke	8B11.20	Whole blood	1.05E-01	3.94E-02	1.57E-01
Cervical cancer	2C77	Cervical tissue	2.50E-01	-8.18E-02	-2.18E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	9.45E-01	5.05E-03	1.31E-02
Chronic hepatitis C	1E51.1	Whole blood	8.24E-01	-2.49E-02	-2.62E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	7.18E-01	-8.92E-02	-2.57E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	9.88E-01	-5.09E-03	-3.17E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.43E-01	1.80E-01	7.82E-01
Colon cancer	2B90	Colon tissue	6.58E-01	-8.32E-03	-3.29E-02
Coronary artery disease	BA80-BA8Z	Peripheral blood	4.76E-01	-4.70E-02	-2.99E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	9.39E-01	-8.28E-02	-3.28E-01
Endometriosis	GA10	Endometrium tissue	8.12E-01	5.57E-02	1.10E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.55E-01	-5.20E-02	-3.76E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.40E-05	-2.90E-01	-1.12E+00
Gastric cancer	2B72	Gastric tissue	4.26E-02	6.12E-01	2.72E+00
Glioblastopma	2A00.00	Nervous tissue	3.07E-75	-9.37E-01	-1.33E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	5.79E-02	-1.02E+00	-3.95E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	3.69E-01	-1.54E-01	-5.04E-01
Head and neck cancer	2D42	Head and neck tissue	1.04E-35	9.79E-01	2.16E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.46E-01	-1.59E-01	-3.06E-01
Huntington's disease	8A01.10	Whole blood	6.34E-01	3.56E-03	4.07E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.26E-02	4.50E-01	1.90E+00
Immunodeficiency	4A00-4A20	Peripheral blood	2.02E-01	5.87E-02	8.11E-01
Influenza	1E30	Whole blood	2.59E-01	1.15E-01	1.26E+00
Interstitial cystitis	GC00.3	Bladder tissue	8.56E-02	3.40E-01	1.43E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.00E-01	1.97E-01	5.36E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.87E-02	2.80E-02	1.74E-01
Ischemic stroke	8B11	Peripheral blood	2.75E-01	4.02E-02	1.82E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.08E-01	1.33E-02	6.48E-02
Lateral sclerosis	8B60.4	Skin	5.23E-02	3.55E-01	1.28E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	7.52E-01	4.73E-02	1.21E-01
Liver cancer	2C12.0	Liver tissue	5.51E-01	-1.82E-01	-7.73E-01
Liver failure	DB99.7-DB99.8	Liver tissue	5.39E-04	6.09E-01	2.15E+00
Lung cancer	2C25	Lung tissue	2.10E-02	-1.05E-01	-2.06E-01
Lupus erythematosus	4A40	Whole blood	1.30E-01	-8.91E-02	-2.00E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	7.99E-01	6.84E-02	1.49E-01
Major depressive disorder	6A70-6A7Z	Whole blood	2.63E-01	-3.01E-03	-1.09E-02
Melanoma	2C30	Skin	7.53E-02	-1.99E-01	-3.16E-01
Multiple myeloma	2A83.1	Peripheral blood	8.57E-01	1.14E-02	8.92E-02
Multiple myeloma	2A83.1	Bone marrow	2.07E-02	-1.52E-01	-7.63E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	6.65E-01	-7.90E-02	-3.11E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	5.47E-01	-3.93E-02	-1.81E-01
Myelofibrosis	2A20.2	Whole blood	2.77E-01	-8.98E-02	-6.57E-01
Myocardial infarction	BA41-BA50	Peripheral blood	7.37E-02	2.62E-01	6.15E-01
Myopathy	8C70.6	Muscle tissue	1.03E-02	3.48E-01	1.19E+00
Neonatal sepsis	KA60	Whole blood	1.76E-08	-2.45E-01	-1.11E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	6.40E-07	4.17E-01	1.89E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.68E-01	-4.50E-03	-4.60E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.79E-01	-3.17E-01	-3.40E-01
Olive pollen allergy	CA08.00	Peripheral blood	8.22E-01	1.12E-01	4.83E-01
Oral cancer	2B6E	Oral tissue	3.95E-03	2.77E-01	5.69E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	6.25E-02	-4.65E-01	-8.09E-01
Osteoporosis	FB83.1	Bone marrow	8.31E-01	1.77E-01	3.13E-01
Ovarian cancer	2C73	Ovarian tissue	1.58E-03	-6.90E-01	-2.30E+00
Pancreatic cancer	2C10	Pancreas	5.99E-02	-2.29E-01	-4.12E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	1.54E-01	-5.03E-02	-2.67E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	3.58E-02	-5.87E-02	-4.70E-01
Pituitary cancer	2D12	Pituitary tissue	6.94E-04	-7.81E-01	-1.40E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	3.47E-04	-1.08E+00	-1.69E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	5.48E-01	3.38E-02	2.55E-01
Polycythemia vera	2A20.4	Whole blood	9.89E-02	3.27E-02	2.40E-01
Pompe disease	5C51.3	Biceps muscle	2.85E-01	-9.22E-02	-2.97E-01
Preterm birth	KA21.4Z	Myometrium	3.04E-02	-8.74E-01	-1.91E+00
Prostate cancer	2C82	Prostate	1.72E-01	-2.35E-01	-5.67E-01
Psoriasis	EA90	Skin	4.59E-17	-3.81E-01	-1.22E+00
Rectal cancer	2B92	Rectal colon tissue	4.49E-01	-1.26E-01	-9.65E-01
Renal cancer	2C90-2C91	Kidney	2.22E-02	-5.72E-01	-1.08E+00
Retinoblastoma	2D02.2	Uvea	1.96E-03	7.12E-01	1.09E+00
Rheumatoid arthritis	FA20	Synovial tissue	4.27E-02	-2.79E-01	-1.02E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	1.83E-01	4.83E-02	2.18E-01
Schizophrenia	6A20	Prefrontal cortex	3.94E-02	-1.49E-01	-1.64E-01
Schizophrenia	6A20	Superior temporal cortex	4.02E-01	-1.23E-01	-3.22E-01
Scleroderma	4A42.Z	Whole blood	9.37E-01	9.70E-02	2.63E-01
Seizure	8A60-8A6Z	Whole blood	8.38E-01	-6.72E-02	-2.88E-01
Sensitive skin	EK0Z	Skin	4.61E-01	2.25E-01	1.10E+00
Sepsis with septic shock	1G41	Whole blood	1.52E-06	-9.68E-02	-4.23E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	9.48E-02	3.40E-01	1.10E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	3.65E-01	1.76E-01	8.38E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	5.96E-02	4.50E-01	2.08E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.57E-02	4.25E-01	2.87E+00
Skin cancer	2C30-2C3Z	Skin	8.14E-80	-1.23E+00	-2.78E+00
Thrombocythemia	3B63	Whole blood	7.12E-01	2.95E-02	2.58E-01
Thrombocytopenia	3B64	Whole blood	8.47E-01	1.15E-01	4.17E-01
Thyroid cancer	2D10	Thyroid	1.43E-32	-6.02E-01	-1.98E+00
Tibial muscular dystrophy	8C75	Muscle tissue	3.30E-01	2.69E-01	4.35E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	8.40E-02	-4.47E-01	-3.97E+00
Type 2 diabetes	5A11	Liver tissue	6.67E-01	-2.97E-02	-3.65E-01
Ureter cancer	2C92	Urothelium	6.85E-01	-3.67E-02	-2.12E-01
Uterine cancer	2C78	Endometrium tissue	5.65E-01	1.61E-01	2.68E-01
Vitiligo	ED63.0	Skin	7.13E-01	1.91E-02	1.64E-01