Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT0OA2B)

• DTP Name: Cation-chloride cotransporter 9 (SLC12A8) DTP Info
• Gene Name: CCC9

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	4.01E-08	1.32E-01	7.63E-01
Adrenocortical carcinoma	2D11.Z	Kidney	2.57E-05	2.10E-01	1.02E+00
Alopecia	ED70	Skin from scalp	2.16E-01	-4.82E-02	-1.14E-01
Alzheimer's disease	8A20	Entorhinal cortex	6.85E-05	-1.63E-01	-4.44E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	3.88E-01	5.40E-01	4.20E-01
Aortic stenosis	BB70	Calcified aortic valve	1.19E-01	-2.38E-02	-5.15E-02
Apnea	7A40	Hyperplastic tonsil	4.32E-02	-1.23E+00	-7.15E-01
Arthropathy	FA00-FA5Z	Peripheral blood	1.16E-01	4.38E-02	3.54E-01
Asthma	CA23	Nasal and bronchial airway	2.60E-04	4.27E-01	5.87E-01
Atopic dermatitis	EA80	Skin	5.66E-02	3.32E-01	1.02E+00
Autism	6A02	Whole blood	7.85E-02	-4.67E-02	-2.45E-01
Autoimmune uveitis	9A96	Peripheral monocyte	2.95E-01	2.39E-01	1.35E+00
Autosomal dominant monocytopenia	4B04	Whole blood	8.94E-01	-1.01E-02	-7.09E-02
Bacterial infection of gingival	1C1H	Gingival tissue	1.84E-10	8.21E-01	9.51E-01
Batten disease	5C56.1	Whole blood	1.04E-01	1.78E-01	8.13E-01
Behcet's disease	4A62	Peripheral blood	1.04E-01	6.39E-02	2.93E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	7.13E-01	-1.35E-01	-3.51E-01
Bladder cancer	2C94	Bladder tissue	9.11E-09	1.63E+00	5.17E+00
Breast cancer	2C60-2C6Z	Breast tissue	3.25E-152	1.49E+00	3.02E+00
Cardioembolic stroke	8B11.20	Whole blood	9.74E-01	2.67E-02	5.69E-02
Cervical cancer	2C77	Cervical tissue	8.56E-03	4.25E-01	1.03E+00
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.02E-01	5.46E-03	2.01E-02
Chronic hepatitis C	1E51.1	Whole blood	1.25E-01	-4.43E-02	-3.78E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	9.23E-01	-5.24E-02	-1.24E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.02E-01	3.61E-02	1.17E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.12E-03	5.53E-01	2.72E+00
Colon cancer	2B90	Colon tissue	8.04E-34	5.63E-01	1.14E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.52E-01	9.06E-03	1.84E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.41E-01	-3.15E-01	-4.46E-01
Endometriosis	GA10	Endometrium tissue	7.68E-03	8.27E-02	1.88E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	9.55E-01	-1.36E-03	-1.01E-02
Familial hypercholesterolemia	5C80.00	Whole blood	1.99E-02	9.86E-02	5.97E-01
Gastric cancer	2B72	Gastric tissue	2.24E-01	1.16E+00	1.17E+00
Glioblastopma	2A00.00	Nervous tissue	2.38E-22	-5.17E-01	-8.19E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	4.25E-02	4.77E-01	8.34E-01
Head and neck cancer	2D42	Head and neck tissue	5.05E-17	8.28E-01	1.46E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	8.66E-01	1.81E-02	5.34E-02
Huntington's disease	8A01.10	Whole blood	7.66E-01	4.43E-02	2.77E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	7.40E-01	-3.11E-01	-5.20E-01
Immunodeficiency	4A00-4A20	Peripheral blood	5.61E-03	1.61E-01	1.28E+00
Influenza	1.00E+30	Whole blood	4.61E-02	2.99E-01	1.93E+00
Interstitial cystitis	GC00.3	Bladder tissue	8.83E-04	6.10E-01	2.76E+00
Intracranial aneurysm	8B01.0	Intracranial artery	9.75E-04	1.09E+00	2.80E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.06E-01	1.25E-01	3.87E-01
Ischemic stroke	8B11	Peripheral blood	2.49E-01	4.20E-02	4.72E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	8.47E-01	1.43E-02	2.83E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	7.41E-01	9.89E-02	2.44E-01
Lateral sclerosis	8B60.4	Skin	1.76E-02	3.59E-01	1.46E+00
Liver cancer	2C12.0	Liver tissue	1.04E-02	3.54E-01	6.01E-01
Liver failure	DB99.7-DB99.8	Liver tissue	3.39E-02	-3.61E-01	-4.34E-01
Lung cancer	2C25	Lung tissue	3.60E-103	1.52E+00	3.14E+00
Lupus erythematosus	4A40	Whole blood	9.79E-07	7.69E-02	2.68E-01
Major depressive disorder	6A70-6A7Z	Whole blood	9.90E-02	7.30E-02	2.67E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	6.85E-01	7.87E-02	2.01E-01
Melanoma	2C30	Skin	9.80E-03	-7.88E-01	-7.59E-01
Multiple myeloma	2A83.1	Bone marrow	1.88E-03	9.06E-02	8.55E-01
Multiple myeloma	2A83.1	Peripheral blood	9.96E-01	-7.04E-02	-3.15E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.92E-01	2.36E-01	7.91E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.91E-03	-1.39E-01	-7.70E-01
Myelofibrosis	2A20.2	Whole blood	3.30E-01	-4.48E-03	-2.91E-02
Myocardial infarction	BA41-BA50	Peripheral blood	9.65E-02	9.46E-02	2.17E-01
Myopathy	8C70.6	Muscle tissue	4.71E-01	4.03E-03	2.74E-02
Neonatal sepsis	KA60	Whole blood	7.07E-03	3.11E-02	1.59E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.69E-03	2.11E-01	7.34E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.87E-01	2.63E-02	5.12E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.37E-01	-1.10E+00	-7.51E-01
Olive pollen allergy	CA08.00	Peripheral blood	4.71E-01	-1.58E-01	-2.77E-01
Oral cancer	2B6E	Oral tissue	4.92E-01	-1.83E-02	-1.44E-02
Osteoarthritis	FA00-FA0Z	Synovial tissue	2.14E-01	2.04E-01	3.62E-01
Osteoporosis	FB83.1	Bone marrow	7.27E-02	-3.08E-01	-1.41E+00
Ovarian cancer	2C73	Ovarian tissue	1.47E-02	1.85E+00	1.34E+00
Pancreatic cancer	2C10	Pancreas	2.15E-05	9.05E-01	1.41E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	3.79E-01	-1.38E-01	-6.83E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.16E-02	9.92E-02	5.57E-01
Pituitary cancer	2D12	Pituitary tissue	4.71E-02	2.75E-02	8.81E-02
Pituitary gonadotrope tumour	2D12	Pituitary tissue	6.52E-03	1.00E+00	2.70E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	7.63E-01	4.51E-02	3.67E-01
Polycythemia vera	2A20.4	Whole blood	8.81E-01	-1.22E-02	-6.35E-02
Pompe disease	5C51.3	Biceps muscle	4.74E-01	8.38E-03	5.29E-02
Preterm birth	KA21.4Z	Myometrium	9.77E-01	-4.37E-01	-3.87E-01
Prostate cancer	2C82	Prostate	1.53E-08	1.96E+00	2.09E+00
Psoriasis	EA90	Skin	1.11E-17	4.54E-01	8.19E-01
Rectal cancer	2B92	Rectal colon tissue	8.94E-02	3.30E-01	6.33E-01
Renal cancer	2C90-2C91	Kidney	7.99E-03	1.46E-01	3.47E-01
Retinoblastoma	2D02.2	Uvea	6.74E-03	2.29E-01	3.62E+00
Rheumatoid arthritis	FA20	Synovial tissue	5.38E-06	1.04E+00	3.10E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.95E-01	-2.85E-02	-1.33E-01
Schizophrenia	6A20	Prefrontal cortex	3.35E-02	-3.51E-01	-4.71E-01
Schizophrenia	6A20	Superior temporal cortex	9.55E-01	-5.85E-02	-2.40E-01
Scleroderma	4A42.Z	Whole blood	6.67E-02	8.75E-02	7.26E-01
Seizure	8A60-8A6Z	Whole blood	5.81E-01	1.15E-01	2.79E-01
Sensitive skin	EK0Z	Skin	6.91E-01	3.27E-01	7.21E-01
Sepsis with septic shock	1G41	Whole blood	8.71E-10	1.42E-01	5.73E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	9.39E-02	-9.20E-02	-6.18E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	3.56E-01	9.52E-02	7.02E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	6.18E-01	1.56E-02	3.63E-02
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.54E-02	-3.55E-01	-1.22E+00
Skin cancer	2C30-2C3Z	Skin	1.01E-15	6.01E-01	6.85E-01
Thrombocythemia	3B63	Whole blood	9.79E-01	-5.37E-03	-2.70E-02
Thrombocytopenia	3B64	Whole blood	2.18E-01	7.27E-03	3.71E-02
Thyroid cancer	2D10	Thyroid	4.59E-16	-6.70E-01	-1.02E+00
Tibial muscular dystrophy	8C75	Muscle tissue	1.12E-02	-2.42E-01	-1.16E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.10E-01	-7.28E-01	-1.19E+00
Type 2 diabetes	5A11	Liver tissue	6.45E-01	2.42E-01	5.72E-01
Ureter cancer	2C92	Urothelium	2.07E-01	-9.10E-02	-2.22E-01
Uterine cancer	2C78	Endometrium tissue	1.36E-12	7.41E-01	9.88E-01
Vitiligo	ED63.0	Skin	3.83E-01	-3.68E-01	-4.56E-01