Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT0YAUQ)

• DTP Name: Mitochondrial 2-oxoglutarate/malate carrier (SLC25A11) DTP Info
• Gene Name: OGC

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	7.43E-01	1.07E-01	1.97E-01
Adrenocortical carcinoma	2D11.Z	Kidney	6.84E-01	-2.49E-02	-9.19E-02
Alopecia	ED70	Skin from scalp	8.00E-01	3.74E-02	1.78E-01
Alzheimer's disease	8A20	Entorhinal cortex	4.46E-12	-4.34E-01	-1.27E+00
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.97E-01	1.70E-01	8.36E-01
Aortic stenosis	BB70	Calcified aortic valve	2.87E-01	1.78E-01	3.67E-01
Apnea	7A40	Hyperplastic tonsil	6.52E-01	-3.75E-02	-1.00E-01
Arthropathy	FA00-FA5Z	Peripheral blood	2.49E-02	-2.00E-01	-1.02E+00
Asthma	CA23	Nasal and bronchial airway	2.23E-06	3.71E-01	4.71E-01
Atopic dermatitis	EA80	Skin	5.22E-02	2.71E-01	7.67E-01
Autism	6A02	Whole blood	1.36E-02	-2.16E-01	-5.50E-01
Autoimmune uveitis	9A96	Peripheral monocyte	2.02E-01	-1.54E-01	-8.49E-01
Autosomal dominant monocytopenia	4B04	Whole blood	1.51E-01	-9.52E-01	-1.48E+00
Bacterial infection of gingival	1C1H	Gingival tissue	2.07E-03	9.80E-02	3.28E-01
Batten disease	5C56.1	Whole blood	2.66E-01	-3.11E-01	-1.99E+00
Behcet's disease	4A62	Peripheral blood	4.72E-01	6.32E-03	1.98E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.25E-01	-9.19E-02	-4.75E-01
Bladder cancer	2C94	Bladder tissue	1.92E-02	-1.66E-01	-7.62E-01
Breast cancer	2C60-2C6Z	Breast tissue	1.40E-07	-1.99E-01	-4.76E-01
Cardioembolic stroke	8B11.20	Whole blood	1.25E-02	1.54E-01	7.80E-01
Cervical cancer	2C77	Cervical tissue	1.06E-01	-1.31E-01	-2.40E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.62E-01	-1.48E-01	-3.31E-01
Chronic hepatitis C	1E51.1	Whole blood	5.76E-01	7.92E-02	3.32E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.90E-01	-1.40E-01	-3.58E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	6.85E-02	-5.90E-02	-1.41E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	9.97E-01	-1.19E-02	-3.22E-02
Colon cancer	2B90	Colon tissue	5.63E-53	-6.46E-01	-1.78E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.06E-02	7.04E-01	2.49E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	3.29E-01	8.37E-02	1.86E-01
Endometriosis	GA10	Endometrium tissue	3.56E-01	4.42E-02	7.62E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	2.35E-01	-4.34E-02	-1.82E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.96E-05	4.62E-01	1.39E+00
Gastric cancer	2B72	Gastric tissue	8.82E-01	8.12E-02	2.72E-01
Glioblastopma	2A00.00	Nervous tissue	5.14E-77	-6.25E-01	-1.23E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	9.68E-03	7.61E-01	1.16E+00
Head and neck cancer	2D42	Head and neck tissue	1.31E-03	-8.31E-02	-2.49E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	6.05E-01	-7.76E-02	-1.63E-01
Huntington's disease	8A01.10	Whole blood	8.68E-01	-1.68E-01	-4.99E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.07E-01	1.53E-01	3.69E-01
Immunodeficiency	4A00-4A20	Peripheral blood	8.91E-03	1.53E-01	1.92E+00
Influenza	1.00E+30	Whole blood	6.92E-04	-8.05E-01	-3.20E+00
Interstitial cystitis	GC00.3	Bladder tissue	6.62E-01	2.48E-02	1.10E-01
Intracranial aneurysm	8B01.0	Intracranial artery	7.44E-02	2.00E-01	4.38E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.10E-02	-1.57E-01	-4.88E-01
Ischemic stroke	8B11	Peripheral blood	2.22E-01	-6.54E-02	-4.15E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.07E-02	-9.77E-02	-2.39E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	6.11E-01	-4.78E-02	-7.66E-02
Lateral sclerosis	8B60.4	Skin	6.84E-02	1.17E-01	6.70E-01
Liver cancer	2C12.0	Liver tissue	5.53E-04	-2.43E-01	-6.09E-01
Liver failure	DB99.7-DB99.8	Liver tissue	3.86E-02	-3.75E-01	-9.45E-01
Lung cancer	2C25	Lung tissue	8.78E-01	-4.99E-02	-1.37E-01
Lupus erythematosus	4A40	Whole blood	2.35E-08	4.16E-01	8.69E-01
Major depressive disorder	6A70-6A7Z	Whole blood	6.97E-01	-1.52E-03	-6.63E-03
Major depressive disorder	6A70-6A7Z	Hippocampus	6.84E-01	3.22E-02	2.08E-01
Melanoma	2C30	Skin	2.03E-01	-9.12E-02	-1.37E-01
Multiple myeloma	2A83.1	Bone marrow	1.45E-04	2.93E-01	1.93E+00
Multiple myeloma	2A83.1	Peripheral blood	4.80E-01	-3.68E-01	-6.52E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.82E-01	-2.26E-01	-3.01E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	8.38E-01	1.28E-01	3.01E-01
Myelofibrosis	2A20.2	Whole blood	3.01E-08	-2.29E-01	-1.13E+00
Myocardial infarction	BA41-BA50	Peripheral blood	1.97E-02	-1.47E-01	-2.77E-01
Myopathy	8C70.6	Muscle tissue	8.11E-02	-3.52E-01	-1.73E+00
Neonatal sepsis	KA60	Whole blood	1.52E-08	3.14E-01	1.08E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	3.87E-01	2.24E-02	6.19E-02
Non-alcoholic fatty liver disease	DB92	Liver tissue	6.81E-01	-2.30E-01	-4.53E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.26E-02	2.26E-01	1.21E+00
Olive pollen allergy	CA08.00	Peripheral blood	1.79E-01	2.04E-01	3.64E-01
Oral cancer	2B6E	Oral tissue	7.47E-03	-1.68E-01	-1.86E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	9.66E-01	-6.24E-01	-4.69E-01
Osteoporosis	FB83.1	Bone marrow	8.87E-01	1.42E-01	4.45E-01
Ovarian cancer	2C73	Ovarian tissue	2.61E-02	2.88E-01	7.84E-01
Pancreatic cancer	2C10	Pancreas	1.80E-01	1.54E-01	3.45E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	5.19E-01	-1.83E-01	-3.69E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	9.45E-05	2.24E-01	1.24E+00
Pituitary cancer	2D12	Pituitary tissue	1.94E-06	9.46E-01	2.91E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.73E-05	5.78E-01	1.82E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.00E-01	3.02E-02	8.21E-02
Polycythemia vera	2A20.4	Whole blood	1.60E-16	-3.06E-01	-1.71E+00
Pompe disease	5C51.3	Biceps muscle	1.41E-01	-1.40E-01	-8.86E-01
Preterm birth	KA21.4Z	Myometrium	4.03E-01	-1.17E-01	-6.38E-01
Prostate cancer	2C82	Prostate	1.55E-01	-5.16E-03	-9.89E-03
Psoriasis	EA90	Skin	1.32E-02	1.50E-01	3.88E-01
Rectal cancer	2B92	Rectal colon tissue	1.14E-05	-7.03E-01	-3.93E+00
Renal cancer	2C90-2C91	Kidney	3.25E-05	-7.61E-01	-2.64E+00
Retinoblastoma	2D02.2	Uvea	6.48E-03	4.49E-01	2.33E+00
Rheumatoid arthritis	FA20	Synovial tissue	5.83E-02	1.37E+00	1.26E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	2.67E-01	-2.74E-02	-2.16E-01
Schizophrenia	6A20	Prefrontal cortex	5.83E-05	-2.10E-01	-7.41E-01
Schizophrenia	6A20	Superior temporal cortex	3.91E-02	-3.20E-01	-1.08E+00
Scleroderma	4A42.Z	Whole blood	1.96E-02	-7.26E-02	-7.13E-01
Seizure	8A60-8A6Z	Whole blood	8.28E-01	1.29E-01	4.39E-01
Sensitive skin	EK0Z	Skin	4.43E-01	-1.05E-01	-4.66E-01
Sepsis with septic shock	1G41	Whole blood	5.26E-27	4.09E-01	1.40E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.57E-01	-2.32E-01	-9.61E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	2.18E-01	6.77E-02	4.35E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	7.98E-01	-2.96E-01	-1.02E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	5.62E-01	-1.64E-01	-1.48E+00
Skin cancer	2C30-2C3Z	Skin	5.62E-01	1.12E-01	2.36E-01
Thrombocythemia	3B63	Whole blood	2.96E-10	-2.99E-01	-1.43E+00
Thrombocytopenia	3B64	Whole blood	6.53E-01	3.41E-01	4.24E-01
Thyroid cancer	2D10	Thyroid	4.78E-01	-6.12E-02	-2.38E-01
Tibial muscular dystrophy	8C75	Muscle tissue	9.44E-02	-3.23E-01	-6.13E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	7.71E-03	-8.56E-01	-6.71E+00
Type 2 diabetes	5A11	Liver tissue	1.63E-01	-7.21E-02	-4.13E-01
Ureter cancer	2C92	Urothelium	3.99E-01	-1.05E-01	-4.96E-01
Uterine cancer	2C78	Endometrium tissue	1.18E-20	-6.30E-01	-8.64E-01
Vitiligo	ED63.0	Skin	7.25E-01	-6.51E-02	-2.35E-01