Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT2EG60)

• DTP Name: Organic cation/carnitine transporter 1 (SLC22A4) DTP Info
• Gene Name: OCTN1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.75E-47	-1.48E+00	-1.98E+00
Adrenocortical carcinoma	2D11.Z	Kidney	1.78E-01	-1.92E-01	-2.93E-01
Alopecia	ED70	Skin from scalp	1.25E-04	4.44E-01	7.66E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.26E-01	5.94E-02	1.21E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.66E-01	-3.52E-02	-7.64E-02
Aortic stenosis	BB70	Calcified aortic valve	8.74E-01	7.78E-02	1.22E-01
Apnea	7A40	Hyperplastic tonsil	9.55E-02	-1.66E-01	-6.09E-01
Arthropathy	FA00-FA5Z	Peripheral blood	4.48E-03	5.13E-01	1.36E+00
Asthma	CA23	Nasal and bronchial airway	1.07E-02	-7.67E-02	-8.08E-02
Atopic dermatitis	EA80	Skin	5.08E-02	-1.31E-01	-2.38E-01
Autism	6A02	Whole blood	9.33E-01	-1.97E-02	-2.70E-02
Autoimmune uveitis	9A96	Peripheral monocyte	5.66E-01	-4.64E-01	-3.02E-01
Autosomal dominant monocytopenia	4B04	Whole blood	1.60E-01	-3.15E-01	-9.09E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.47E-05	1.60E-01	5.53E-01
Batten disease	5C56.1	Whole blood	2.75E-01	4.92E-01	8.42E-01
Behcet's disease	4A62	Peripheral blood	4.57E-01	3.26E-01	6.66E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	3.96E-01	-1.36E-02	-3.66E-02
Bladder cancer	2C94	Bladder tissue	3.15E-02	3.82E-01	8.60E-01
Breast cancer	2C60-2C6Z	Breast tissue	1.27E-03	5.92E-02	9.10E-02
Cardioembolic stroke	8B11.20	Whole blood	8.55E-11	9.77E-01	2.54E+00
Cervical cancer	2C77	Cervical tissue	1.01E-01	3.29E-01	7.34E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	8.26E-01	4.98E-01	2.34E-01
Chronic hepatitis C	1E51.1	Whole blood	6.05E-01	-5.14E-01	-2.51E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	6.64E-01	-7.95E-02	-9.98E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	8.72E-01	-1.72E-02	-3.45E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	5.74E-03	-1.56E+00	-1.70E+00
Colon cancer	2B90	Colon tissue	7.24E-27	-1.05E+00	-1.17E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	8.05E-01	2.90E-01	2.26E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.00E-01	-4.55E-02	-1.57E-01
Endometriosis	GA10	Endometrium tissue	4.78E-01	8.67E-01	5.49E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.93E-02	-1.35E-01	-6.99E-01
Familial hypercholesterolemia	5C80.00	Whole blood	8.52E-05	-7.93E-01	-1.09E+00
Gastric cancer	2B72	Gastric tissue	1.44E-03	6.97E-01	6.38E+00
Glioblastopma	2A00.00	Nervous tissue	1.46E-111	1.00E+00	2.02E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	5.50E-03	1.34E+00	1.13E+00
Head and neck cancer	2D42	Head and neck tissue	2.76E-09	-1.20E-01	-3.47E-02
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	5.24E-01	-7.21E-02	-2.42E-01
Huntington's disease	8A01.10	Whole blood	3.17E-01	-6.20E-02	-1.85E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	6.83E-01	3.34E-01	3.53E-01
Immunodeficiency	4A00-4A20	Peripheral blood	2.47E-02	6.41E-02	4.47E-01
Influenza	1.00E+30	Whole blood	6.61E-01	-3.56E-01	-4.88E-01
Interstitial cystitis	GC00.3	Bladder tissue	1.74E-02	9.22E-01	2.53E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.88E-01	7.34E-01	6.95E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	8.04E-01	2.33E-02	5.65E-02
Ischemic stroke	8B11	Peripheral blood	6.11E-02	3.97E-01	7.56E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.42E-01	3.95E-01	2.67E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	1.08E-01	-2.20E-01	-4.82E-01
Lateral sclerosis	8B60.4	Skin	7.22E-01	1.90E-01	1.93E-01
Liver cancer	2C12.0	Liver tissue	1.11E-11	2.22E-01	5.45E-01
Liver failure	DB99.7-DB99.8	Liver tissue	5.43E-01	4.51E-01	6.98E-01
Lung cancer	2C25	Lung tissue	1.48E-19	-1.06E+00	-8.94E-01
Lupus erythematosus	4A40	Whole blood	6.24E-04	5.40E-01	3.30E-01
Major depressive disorder	6A70-6A7Z	Whole blood	2.33E-02	1.91E-01	4.89E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	7.33E-01	-8.58E-02	-2.23E-01
Melanoma	2C30	Skin	1.40E-01	-8.19E-01	-6.47E-01
Multiple myeloma	2A83.1	Bone marrow	4.31E-04	8.88E-02	5.56E-01
Multiple myeloma	2A83.1	Peripheral blood	4.59E-01	8.30E-02	3.35E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.41E-01	-7.96E-02	-1.50E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.15E-06	-4.10E-01	-6.25E-01
Myelofibrosis	2A20.2	Whole blood	9.89E-02	2.70E-01	6.07E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.49E-04	2.26E+00	1.05E+00
Myopathy	8C70.6	Muscle tissue	3.18E-01	5.32E-01	7.72E-01
Neonatal sepsis	KA60	Whole blood	3.27E-17	1.90E+00	1.60E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	5.39E-04	-9.04E-01	-1.71E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.75E-01	4.68E-01	7.07E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.66E-01	-3.76E-02	-4.13E-02
Olive pollen allergy	CA08.00	Peripheral blood	1.59E-01	-9.95E-01	-9.50E-01
Oral cancer	2B6E	Oral tissue	1.71E-07	7.42E-01	1.58E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	2.63E-02	1.09E+00	2.20E+00
Osteoporosis	FB83.1	Bone marrow	5.98E-02	-1.60E+00	-2.10E+00
Ovarian cancer	2C73	Ovarian tissue	8.81E-01	3.44E-01	2.55E-01
Pancreatic cancer	2C10	Pancreas	8.02E-02	2.44E-01	4.59E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	3.72E-02	-7.57E-01	-1.75E+00
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	6.62E-07	2.50E+00	2.86E+00
Pituitary cancer	2D12	Pituitary tissue	2.03E-04	8.41E-01	1.65E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.11E-06	1.99E+00	5.66E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	5.03E-01	-3.26E-02	-1.34E-01
Polycythemia vera	2A20.4	Whole blood	7.64E-19	8.55E-01	1.87E+00
Pompe disease	5C51.3	Biceps muscle	4.69E-01	6.27E-02	1.51E-01
Preterm birth	KA21.4Z	Myometrium	2.51E-01	-5.74E-01	-5.22E-01
Prostate cancer	2C82	Prostate	3.83E-02	-3.39E-01	-3.57E-01
Psoriasis	EA90	Skin	4.95E-01	1.01E-02	1.82E-02
Rectal cancer	2B92	Rectal colon tissue	1.67E-03	-1.27E+00	-2.62E+00
Renal cancer	2C90-2C91	Kidney	5.12E-01	4.81E-01	4.42E-01
Retinoblastoma	2D02.2	Uvea	4.32E-01	3.36E-01	7.13E-01
Rheumatoid arthritis	FA20	Synovial tissue	2.68E-03	3.88E-01	1.18E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	4.04E-01	-2.89E-01	-3.35E-01
Schizophrenia	6A20	Prefrontal cortex	7.97E-02	-6.02E-02	-1.03E-01
Schizophrenia	6A20	Superior temporal cortex	4.84E-01	-4.72E-02	-4.51E-01
Scleroderma	4A42.Z	Whole blood	4.43E-01	2.79E-01	5.26E-01
Seizure	8A60-8A6Z	Whole blood	8.59E-01	-1.06E-01	-8.38E-02
Sensitive skin	EK0Z	Skin	1.80E-02	-2.84E-01	-8.88E-01
Sepsis with septic shock	1G41	Whole blood	3.04E-72	2.08E+00	2.58E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	4.09E-01	3.89E-01	1.20E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	6.09E-02	1.99E-01	7.23E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.73E-01	2.63E-02	3.07E-02
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.32E-01	3.11E-01	4.51E-01
Skin cancer	2C30-2C3Z	Skin	7.80E-02	-2.10E-01	-2.94E-01
Thrombocythemia	3B63	Whole blood	3.30E-02	3.27E-01	7.20E-01
Thrombocytopenia	3B64	Whole blood	3.85E-01	1.78E-02	1.20E-01
Thyroid cancer	2D10	Thyroid	4.81E-48	8.29E-01	2.89E+00
Tibial muscular dystrophy	8C75	Muscle tissue	1.87E-09	1.52E+00	3.41E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.97E-02	7.60E-01	2.97E+00
Type 2 diabetes	5A11	Liver tissue	6.93E-01	-4.89E-02	-1.64E-01
Ureter cancer	2C92	Urothelium	2.81E-02	-7.52E-02	-1.86E-01
Uterine cancer	2C78	Endometrium tissue	5.97E-05	-3.33E-01	-3.90E-01
Vitiligo	ED63.0	Skin	9.19E-01	-3.39E-02	-3.77E-02