Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT3HUVD)

• DTP Name: Organic cation/carnitine transporter 2 (SLC22A5) DTP Info
• Gene Name: OCTN2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.81E-06	1.17E-01	4.40E-01
Adrenocortical carcinoma	2D11.Z	Kidney	7.94E-02	9.74E-02	5.06E-01
Alopecia	ED70	Skin from scalp	2.98E-01	5.46E-02	3.68E-01
Alzheimer's disease	8A20	Entorhinal cortex	3.49E-09	1.50E-01	6.50E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	4.16E-01	9.29E-02	4.34E-01
Aortic stenosis	BB70	Calcified aortic valve	3.47E-02	-2.55E-01	-1.10E+00
Apnea	7A40	Hyperplastic tonsil	8.12E-01	-6.68E-02	-6.34E-01
Arthropathy	FA00-FA5Z	Peripheral blood	8.66E-01	-1.18E-02	-7.55E-02
Asthma	CA23	Nasal and bronchial airway	2.90E-03	1.58E-01	3.11E-01
Atopic dermatitis	EA80	Skin	1.87E-02	1.28E-01	8.58E-01
Autism	6A02	Whole blood	9.97E-01	2.67E-02	1.20E-01
Autoimmune uveitis	9A96	Peripheral monocyte	2.46E-01	4.78E-01	9.83E-01
Autosomal dominant monocytopenia	4B04	Whole blood	7.23E-01	-2.40E-02	-1.36E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.06E-03	-7.16E-02	-4.39E-01
Batten disease	5C56.1	Whole blood	4.29E-01	1.18E-01	5.66E-01
Behcet's disease	4A62	Peripheral blood	2.44E-01	6.64E-02	2.72E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	9.67E-02	2.74E-02	1.83E-01
Bladder cancer	2C94	Bladder tissue	5.43E-02	-3.78E-01	-1.49E+00
Breast cancer	2C60-2C6Z	Breast tissue	4.98E-05	1.36E-01	4.34E-01
Cardioembolic stroke	8B11.20	Whole blood	1.23E-01	7.37E-02	4.08E-01
Cervical cancer	2C77	Cervical tissue	6.36E-06	-3.95E-01	-1.34E+00
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	2.74E-01	-5.61E-02	-3.67E-01
Chronic hepatitis C	1E51.1	Whole blood	9.43E-01	-4.75E-02	-4.16E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.23E-01	7.41E-03	4.50E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.93E-01	3.10E-02	1.80E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.88E-03	-2.93E-01	-1.16E+00
Colon cancer	2B90	Colon tissue	3.05E-73	-1.00E+00	-2.60E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.46E-01	-1.19E-01	-1.68E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.26E-01	-2.92E-02	-2.11E-01
Endometriosis	GA10	Endometrium tissue	2.01E-01	-1.03E-01	-2.70E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	2.76E-02	8.97E-02	4.78E-01
Familial hypercholesterolemia	5C80.00	Whole blood	8.88E-04	2.80E-01	1.44E+00
Gastric cancer	2B72	Gastric tissue	1.77E-01	-4.21E-01	-1.55E+00
Glioblastopma	2A00.00	Nervous tissue	1.49E-04	1.13E-01	3.47E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	5.70E-02	-3.23E-01	-6.60E-01
Head and neck cancer	2D42	Head and neck tissue	2.25E-13	-4.27E-01	-9.40E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.06E-01	3.94E-02	2.70E-01
Huntington's disease	8A01.10	Whole blood	5.19E-01	-8.06E-02	-5.45E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.53E-02	2.89E-01	2.12E+00
Immunodeficiency	4A00-4A20	Peripheral blood	7.39E-01	-2.95E-02	-3.28E-01
Influenza	1.00E+30	Whole blood	1.06E-01	2.03E-01	1.33E+00
Interstitial cystitis	GC00.3	Bladder tissue	2.83E-06	-8.45E-01	-5.82E+00
Intracranial aneurysm	8B01.0	Intracranial artery	6.33E-02	2.07E-01	8.24E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	3.56E-01	2.89E-03	1.51E-02
Ischemic stroke	8B11	Peripheral blood	2.07E-02	5.99E-02	3.78E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.15E-02	6.11E-02	2.66E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	2.66E-01	2.85E-02	1.30E-01
Lateral sclerosis	8B60.4	Skin	5.23E-01	1.45E-01	7.28E-01
Liver cancer	2C12.0	Liver tissue	7.04E-12	2.58E-01	1.20E+00
Liver failure	DB99.7-DB99.8	Liver tissue	5.40E-02	-1.91E-01	-1.57E+00
Lung cancer	2C25	Lung tissue	9.11E-05	4.75E-02	2.24E-01
Lupus erythematosus	4A40	Whole blood	1.37E-01	8.70E-02	2.98E-01
Major depressive disorder	6A70-6A7Z	Whole blood	7.02E-01	2.51E-02	1.23E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	1.13E-01	-5.69E-03	-4.16E-02
Melanoma	2C30	Skin	1.13E-02	-4.16E-01	-8.00E-01
Multiple myeloma	2A83.1	Bone marrow	4.88E-05	3.23E-01	2.52E+00
Multiple myeloma	2A83.1	Peripheral blood	1.59E-01	-1.16E-01	-4.43E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.02E-01	-1.34E-02	-2.51E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.68E-04	8.15E-02	3.54E-01
Myelofibrosis	2A20.2	Whole blood	4.90E-01	-3.06E-02	-2.46E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.15E-02	-3.81E-01	-6.88E-01
Myopathy	8C70.6	Muscle tissue	3.73E-01	-1.60E-01	-2.94E-01
Neonatal sepsis	KA60	Whole blood	4.29E-01	-2.24E-02	-1.06E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	9.94E-02	-1.79E-01	-5.81E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.68E-01	-1.94E-02	-1.15E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.79E-01	-2.52E-01	-8.33E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.55E-03	-4.77E-01	-3.35E+00
Oral cancer	2B6E	Oral tissue	5.45E-02	-1.12E-01	-2.42E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.20E-01	-2.31E-02	-1.18E-01
Osteoporosis	FB83.1	Bone marrow	9.78E-01	-7.47E-02	-3.55E-01
Ovarian cancer	2C73	Ovarian tissue	6.46E-01	1.51E-01	7.17E-01
Pancreatic cancer	2C10	Pancreas	1.96E-03	-4.96E-01	-1.35E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	9.94E-01	1.54E-02	6.61E-02
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	8.76E-01	-4.79E-02	-2.65E-01
Pituitary cancer	2D12	Pituitary tissue	7.26E-02	-1.53E-01	-5.64E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.73E-01	-1.80E-01	-5.69E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	8.03E-02	-9.61E-02	-4.81E-01
Polycythemia vera	2A20.4	Whole blood	4.82E-03	-9.87E-02	-7.40E-01
Pompe disease	5C51.3	Biceps muscle	8.66E-02	3.01E-01	8.96E-01
Preterm birth	KA21.4Z	Myometrium	1.46E-01	1.47E-01	6.29E-01
Prostate cancer	2C82	Prostate	7.18E-01	-1.67E-02	-3.70E-02
Psoriasis	EA90	Skin	8.18E-03	-6.96E-02	-2.86E-01
Rectal cancer	2B92	Rectal colon tissue	1.08E-13	-9.75E-01	-1.19E+01
Renal cancer	2C90-2C91	Kidney	1.36E-01	-2.68E-01	-4.17E-01
Retinoblastoma	2D02.2	Uvea	6.25E-03	3.29E-01	1.62E+00
Rheumatoid arthritis	FA20	Synovial tissue	8.42E-01	-2.12E-01	-4.31E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.78E-02	-5.67E-02	-6.16E-01
Schizophrenia	6A20	Prefrontal cortex	1.15E-01	3.66E-02	1.68E-01
Schizophrenia	6A20	Superior temporal cortex	4.31E-01	4.52E-02	3.51E-01
Scleroderma	4A42.Z	Whole blood	3.53E-01	-1.19E-01	-7.93E-01
Seizure	8A60-8A6Z	Whole blood	8.29E-01	1.32E-02	1.05E-01
Sensitive skin	EK0Z	Skin	6.93E-01	-2.30E-02	-2.11E-01
Sepsis with septic shock	1G41	Whole blood	1.05E-06	-1.02E-01	-4.61E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.37E-01	-1.47E-01	-7.97E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	8.73E-01	-3.28E-02	-2.38E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	2.20E-01	-1.77E-01	-1.89E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.11E-02	-3.93E-01	-2.94E+00
Skin cancer	2C30-2C3Z	Skin	3.76E-01	4.05E-03	1.27E-02
Thrombocythemia	3B63	Whole blood	1.30E-01	-8.33E-03	-7.34E-02
Thrombocytopenia	3B64	Whole blood	7.56E-01	-1.06E-01	-8.07E-01
Thyroid cancer	2D10	Thyroid	1.95E-01	3.38E-02	1.51E-01
Tibial muscular dystrophy	8C75	Muscle tissue	2.16E-05	-6.39E-01	-1.69E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	5.08E-02	3.22E-01	1.59E+00
Type 2 diabetes	5A11	Liver tissue	2.24E-01	-1.14E-01	-8.52E-01
Ureter cancer	2C92	Urothelium	7.54E-01	-4.80E-02	-3.42E-01
Uterine cancer	2C78	Endometrium tissue	2.09E-21	-6.37E-01	-1.21E+00
Vitiligo	ED63.0	Skin	9.42E-01	3.61E-02	3.82E-01