Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT3T2K0)

• DTP Name: Vesicular acetylcholine transporter (SLC18A3) DTP Info
• Gene Name: VACHT

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.31E-01	1.71E-02	8.43E-02
Adrenocortical carcinoma	2D11.Z	Kidney	4.30E-01	6.31E-04	3.16E-03
Alopecia	ED70	Skin from scalp	3.95E-03	-1.15E-01	-4.46E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.64E-01	-6.42E-02	-3.29E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.27E-01	-8.75E-02	-6.29E-01
Aortic stenosis	BB70	Calcified aortic valve	7.55E-01	-2.73E-01	-4.29E-01
Apnea	7A40	Hyperplastic tonsil	1.32E-02	-4.69E-01	-2.58E+00
Arthropathy	FA00-FA5Z	Peripheral blood	3.19E-01	4.98E-02	3.14E-01
Asthma	CA23	Nasal and bronchial airway	3.16E-01	-5.57E-02	-1.29E-01
Atopic dermatitis	EA80	Skin	3.51E-04	1.01E-01	9.39E-01
Autism	6A02	Whole blood	8.63E-01	-2.80E-02	-1.02E-01
Autoimmune uveitis	9A96	Peripheral monocyte	1.26E-06	-3.43E-01	-1.99E+00
Autosomal dominant monocytopenia	4B04	Whole blood	6.93E-01	8.51E-03	6.59E-02
Bacterial infection of gingival	1C1H	Gingival tissue	9.00E-05	1.72E-01	8.01E-01
Batten disease	5C56.1	Whole blood	5.09E-01	5.68E-02	5.13E-01
Behcet's disease	4A62	Peripheral blood	5.94E-01	2.29E-02	8.02E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	2.09E-01	7.88E-02	4.84E-01
Bladder cancer	2C94	Bladder tissue	2.94E-02	5.44E-01	1.46E+00
Breast cancer	2C60-2C6Z	Breast tissue	6.97E-01	1.79E-02	6.08E-02
Cardioembolic stroke	8B11.20	Whole blood	4.86E-01	-4.82E-02	-1.76E-01
Cervical cancer	2C77	Cervical tissue	9.08E-01	-2.71E-02	-1.05E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	9.46E-01	-1.41E-02	-4.99E-02
Chronic hepatitis C	1E51.1	Whole blood	6.53E-01	-2.83E-02	-1.97E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	8.31E-01	1.13E-02	5.13E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	6.94E-06	2.46E-01	1.02E+00
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	4.40E-01	2.11E-02	1.79E-01
Colon cancer	2B90	Colon tissue	1.10E-09	-1.41E-01	-4.92E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.37E-01	6.30E-02	3.91E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	1.71E-01	-1.79E-01	-6.55E-01
Endometriosis	GA10	Endometrium tissue	5.62E-01	2.55E-02	6.98E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	2.07E-02	8.86E-02	5.52E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.93E-01	-1.10E-02	-3.92E-02
Gastric cancer	2B72	Gastric tissue	2.29E-01	-1.90E-01	-7.81E-01
Glioblastopma	2A00.00	Nervous tissue	3.07E-34	-2.76E-01	-1.00E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.92E-04	-4.23E-01	-1.99E+00
Head and neck cancer	2D42	Head and neck tissue	1.65E-01	7.19E-02	3.89E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	7.75E-01	-8.06E-02	-4.13E-01
Huntington's disease	8A01.10	Whole blood	7.45E-01	5.15E-02	1.64E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	4.00E-01	6.17E-04	2.58E-03
Immunodeficiency	4A00-4A20	Peripheral blood	1.03E-03	2.16E-01	2.22E+00
Influenza	1.00E+30	Whole blood	4.25E-02	4.25E-01	2.83E+00
Interstitial cystitis	GC00.3	Bladder tissue	3.93E-01	1.47E-01	9.63E-01
Intracranial aneurysm	8B01.0	Intracranial artery	3.38E-01	-3.16E-02	-1.12E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.85E-01	-2.56E-02	-7.94E-02
Ischemic stroke	8B11	Peripheral blood	1.17E-02	1.91E-01	1.77E+00
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.49E-01	4.40E-02	1.41E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	2.53E-01	-1.52E-01	-1.85E-01
Lateral sclerosis	8B60.4	Skin	8.80E-01	1.53E-02	5.18E-02
Liver cancer	2C12.0	Liver tissue	4.44E-03	-2.14E-01	-7.00E-01
Liver failure	DB99.7-DB99.8	Liver tissue	5.67E-01	-3.82E-02	-2.00E-01
Lung cancer	2C25	Lung tissue	2.71E-03	-9.88E-02	-3.69E-01
Lupus erythematosus	4A40	Whole blood	6.54E-02	-3.24E-02	-9.61E-02
Major depressive disorder	6A70-6A7Z	Whole blood	1.48E-01	1.55E-02	8.12E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	7.95E-01	5.53E-02	3.65E-01
Melanoma	2C30	Skin	3.72E-01	-1.47E-02	-3.76E-02
Multiple myeloma	2A83.1	Bone marrow	1.94E-01	-1.48E-01	-9.30E-01
Multiple myeloma	2A83.1	Peripheral blood	9.70E-01	-5.96E-02	-2.36E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	5.23E-01	1.95E-01	6.97E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.16E-01	-8.47E-02	-3.85E-01
Myelofibrosis	2A20.2	Whole blood	2.27E-02	2.25E-01	1.27E+00
Myocardial infarction	BA41-BA50	Peripheral blood	5.86E-01	7.63E-03	2.18E-02
Myopathy	8C70.6	Muscle tissue	6.25E-03	-2.48E-01	-1.02E+00
Neonatal sepsis	KA60	Whole blood	6.59E-01	-3.29E-03	-9.74E-03
Neuroectodermal tumour	2A00.11	Brain stem tissue	4.54E-03	-9.20E-01	-1.42E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.66E-01	-4.01E-02	-3.61E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.05E-02	2.32E-01	1.42E+00
Olive pollen allergy	CA08.00	Peripheral blood	2.43E-01	1.29E-01	4.14E-01
Oral cancer	2B6E	Oral tissue	6.10E-08	-4.92E-01	-1.62E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	9.92E-02	-4.97E-01	-1.02E+00
Osteoporosis	FB83.1	Bone marrow	4.03E-02	3.27E-01	2.50E+00
Ovarian cancer	2C73	Ovarian tissue	6.19E-01	1.34E-02	6.41E-02
Pancreatic cancer	2C10	Pancreas	5.71E-03	-3.09E-01	-9.25E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	9.87E-01	1.10E-01	2.88E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	8.84E-01	-5.62E-02	-2.61E-01
Pituitary cancer	2D12	Pituitary tissue	1.32E-02	9.63E-02	3.61E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	6.59E-01	-9.45E-02	-3.29E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.58E-01	-8.16E-04	-3.68E-03
Polycythemia vera	2A20.4	Whole blood	1.59E-05	1.85E-01	9.82E-01
Pompe disease	5C51.3	Biceps muscle	4.05E-02	-1.31E-01	-7.17E-01
Preterm birth	KA21.4Z	Myometrium	8.88E-01	2.37E-02	8.80E-02
Prostate cancer	2C82	Prostate	2.43E-01	4.99E-02	1.28E-01
Psoriasis	EA90	Skin	8.20E-02	-6.92E-02	-1.67E-01
Rectal cancer	2B92	Rectal colon tissue	1.47E-01	-2.20E-01	-9.67E-01
Renal cancer	2C90-2C91	Kidney	7.08E-01	8.34E-02	1.98E-01
Retinoblastoma	2D02.2	Uvea	1.36E-04	-3.57E-01	-1.88E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.94E-02	-6.97E-01	-1.15E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.01E-01	-1.57E-02	-1.30E-01
Schizophrenia	6A20	Prefrontal cortex	8.89E-01	8.54E-04	3.09E-03
Schizophrenia	6A20	Superior temporal cortex	5.86E-01	-3.82E-03	-2.46E-02
Scleroderma	4A42.Z	Whole blood	8.42E-01	3.66E-02	2.31E-01
Seizure	8A60-8A6Z	Whole blood	5.77E-01	-7.40E-02	-2.68E-01
Sensitive skin	EK0Z	Skin	2.35E-01	1.05E-01	8.93E-01
Sepsis with septic shock	1G41	Whole blood	9.03E-01	-8.21E-02	-2.46E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	6.82E-01	2.47E-02	1.15E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	5.93E-01	2.49E-01	5.25E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.17E-01	1.82E-02	1.51E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.95E-01	-1.21E-01	-3.38E-01
Skin cancer	2C30-2C3Z	Skin	8.70E-01	-2.61E-02	-6.55E-02
Thrombocythemia	3B63	Whole blood	3.67E-01	2.33E-02	1.36E-01
Thrombocytopenia	3B64	Whole blood	8.05E-01	2.48E-02	6.22E-02
Thyroid cancer	2D10	Thyroid	4.44E-11	2.02E-01	7.34E-01
Tibial muscular dystrophy	8C75	Muscle tissue	2.32E-06	-5.98E-01	-2.08E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	8.61E-01	9.22E-02	4.81E-01
Type 2 diabetes	5A11	Liver tissue	5.80E-02	-1.79E-01	-1.26E+00
Ureter cancer	2C92	Urothelium	6.38E-01	7.00E-02	3.12E-01
Uterine cancer	2C78	Endometrium tissue	4.66E-01	-3.68E-02	-1.19E-01
Vitiligo	ED63.0	Skin	6.67E-01	-1.42E-02	-1.64E-01