Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT61TWI)

• DTP Name: ATP-binding cassette sub-family A member 1 (ABCA1) DTP Info
• Gene Name: ABCA1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	4.76E-05	4.28E-01	5.57E-01
Adrenocortical carcinoma	2D11.Z	Kidney	1.53E-03	-6.39E-01	-1.09E+00
Alopecia	ED70	Skin from scalp	1.30E-03	1.37E-01	5.21E-01
Alzheimer's disease	8A20	Entorhinal cortex	4.68E-05	1.30E-01	2.97E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.82E-01	-1.02E-01	-2.78E-01
Aortic stenosis	BB70	Calcified aortic valve	5.69E-01	8.68E-02	2.96E-01
Apnea	7A40	Hyperplastic tonsil	1.10E-01	-3.20E-01	-9.19E-01
Arthropathy	FA00-FA5Z	Peripheral blood	5.05E-03	4.23E-01	1.34E+00
Asthma	CA23	Nasal and bronchial airway	2.61E-06	4.19E-01	6.42E-01
Atopic dermatitis	EA80	Skin	1.75E-01	-4.79E-02	-1.20E-01
Autism	6A02	Whole blood	8.79E-01	-6.06E-02	-1.84E-01
Autoimmune uveitis	9A96	Peripheral monocyte	4.09E-01	-2.33E-01	-1.51E-01
Autosomal dominant monocytopenia	4B04	Whole blood	1.09E-02	1.36E+00	2.75E+00
Bacterial infection of gingival	1C1H	Gingival tissue	2.93E-05	2.03E-01	7.79E-01
Batten disease	5C56.1	Whole blood	5.29E-01	3.62E-02	2.00E-01
Behcet's disease	4A62	Peripheral blood	4.59E-01	6.64E-02	2.36E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	4.32E-01	8.31E-02	2.31E-01
Bladder cancer	2C94	Bladder tissue	5.39E-08	-4.98E-01	-3.90E+00
Breast cancer	2C60-2C6Z	Breast tissue	2.11E-16	-2.22E-01	-4.63E-01
Cardioembolic stroke	8B11.20	Whole blood	1.62E-08	6.03E-01	1.45E+00
Cervical cancer	2C77	Cervical tissue	4.24E-01	7.38E-02	2.00E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	9.94E-01	8.22E-02	7.66E-02
Chronic hepatitis C	1E51.1	Whole blood	7.13E-01	-1.46E-01	-1.24E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	6.17E-02	-1.81E-01	-7.21E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	5.41E-01	-2.94E-03	-7.55E-03
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	6.00E-02	3.48E-01	8.51E-01
Colon cancer	2B90	Colon tissue	1.91E-21	-2.91E-01	-8.95E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	4.88E-01	-9.63E-02	-3.33E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	9.14E-01	6.39E-02	3.32E-01
Endometriosis	GA10	Endometrium tissue	1.21E-03	3.52E-01	7.12E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.77E-01	5.71E-02	2.68E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.58E-02	-3.34E-01	-9.69E-01
Gastric cancer	2B72	Gastric tissue	6.18E-01	8.11E-02	5.65E-01
Glioblastopma	2A00.00	Nervous tissue	2.76E-167	1.26E+00	2.43E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	4.58E-02	2.93E-01	5.98E-01
Head and neck cancer	2D42	Head and neck tissue	1.31E-31	9.16E-01	1.75E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.16E-01	1.16E-01	2.47E-01
Huntington's disease	8A01.10	Whole blood	3.54E-01	1.39E-01	5.02E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	4.22E-01	-7.61E-02	-1.81E-01
Immunodeficiency	4A00-4A20	Peripheral blood	3.36E-03	9.23E-02	8.38E-01
Influenza	1.00E+30	Whole blood	7.21E-03	-5.80E-01	-4.31E+00
Interstitial cystitis	GC00.3	Bladder tissue	5.61E-01	-7.23E-02	-6.35E-01
Intracranial aneurysm	8B01.0	Intracranial artery	1.29E-02	5.31E-01	1.32E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	7.00E-01	-4.01E-02	-1.32E-01
Ischemic stroke	8B11	Peripheral blood	3.20E-01	3.47E-01	6.86E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.05E-04	2.06E-01	4.78E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	3.73E-01	9.66E-02	3.48E-01
Lateral sclerosis	8B60.4	Skin	1.19E-01	-1.75E-01	-3.98E+00
Liver cancer	2C12.0	Liver tissue	9.87E-05	-3.83E-01	-8.20E-01
Liver failure	DB99.7-DB99.8	Liver tissue	3.86E-02	-6.52E-01	-2.23E+00
Lung cancer	2C25	Lung tissue	2.88E-05	-1.42E-01	-3.98E-01
Lupus erythematosus	4A40	Whole blood	2.15E-12	5.08E-01	8.17E-01
Major depressive disorder	6A70-6A7Z	Whole blood	7.95E-01	2.12E-02	6.53E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	7.65E-01	-2.02E-02	-6.13E-02
Melanoma	2C30	Skin	8.93E-02	3.78E-01	6.24E-01
Multiple myeloma	2A83.1	Bone marrow	1.36E-01	-2.13E-01	-3.79E-01
Multiple myeloma	2A83.1	Peripheral blood	9.00E-01	-9.52E-03	-6.03E-02
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.45E-01	2.26E-01	9.70E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.20E-01	2.39E-03	2.81E-03
Myelofibrosis	2A20.2	Whole blood	1.04E-01	2.30E-01	9.92E-01
Myocardial infarction	BA41-BA50	Peripheral blood	1.76E-08	1.04E+00	1.45E+00
Myopathy	8C70.6	Muscle tissue	3.04E-04	5.18E-01	2.02E+00
Neonatal sepsis	KA60	Whole blood	1.97E-11	5.13E-01	1.13E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	3.58E-01	6.57E-02	2.08E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.11E-02	3.57E-01	8.44E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	4.10E-01	-3.09E-02	-3.61E-02
Olive pollen allergy	CA08.00	Peripheral blood	9.21E-01	1.41E-01	2.23E-01
Oral cancer	2B6E	Oral tissue	1.26E-05	7.89E-01	1.45E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	8.94E-01	9.43E-02	1.55E-01
Osteoporosis	FB83.1	Bone marrow	2.11E-01	2.64E-01	6.34E-01
Ovarian cancer	2C73	Ovarian tissue	7.87E-01	-1.62E-01	-2.86E-01
Pancreatic cancer	2C10	Pancreas	5.27E-02	6.00E-01	9.15E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	6.39E-01	3.00E-01	6.04E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	6.36E-02	1.82E-01	8.01E-01
Pituitary cancer	2D12	Pituitary tissue	3.96E-01	2.42E-01	8.68E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	9.16E-01	-9.99E-02	-4.13E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	9.13E-01	-8.43E-02	-2.97E-01
Polycythemia vera	2A20.4	Whole blood	1.76E-05	4.23E-01	1.75E+00
Pompe disease	5C51.3	Biceps muscle	8.81E-02	-3.01E-01	-1.16E+00
Preterm birth	KA21.4Z	Myometrium	9.86E-01	-4.76E-01	-5.03E-01
Prostate cancer	2C82	Prostate	3.12E-01	-1.30E-01	-2.52E-01
Psoriasis	EA90	Skin	9.11E-01	5.32E-02	1.42E-01
Rectal cancer	2B92	Rectal colon tissue	3.31E-01	-1.38E-01	-4.81E-01
Renal cancer	2C90-2C91	Kidney	2.70E-06	7.53E-01	2.62E+00
Retinoblastoma	2D02.2	Uvea	1.74E-08	1.67E+00	3.59E+00
Rheumatoid arthritis	FA20	Synovial tissue	3.66E-02	3.09E-01	1.06E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	1.25E-01	9.46E-02	2.86E-01
Schizophrenia	6A20	Prefrontal cortex	3.28E-02	1.12E-01	3.57E-01
Schizophrenia	6A20	Superior temporal cortex	1.26E-01	2.46E-01	8.82E-01
Scleroderma	4A42.Z	Whole blood	1.04E-05	4.19E-01	2.59E+00
Seizure	8A60-8A6Z	Whole blood	7.44E-01	2.84E-01	4.30E-01
Sensitive skin	EK0Z	Skin	2.78E-01	-6.01E-02	-4.70E-01
Sepsis with septic shock	1G41	Whole blood	1.14E-38	5.74E-01	1.37E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.95E-01	-2.67E-02	-1.00E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.96E-02	-1.38E-01	-1.27E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	7.91E-01	2.70E-01	9.09E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.09E-01	4.12E-01	1.69E+00
Skin cancer	2C30-2C3Z	Skin	1.48E-06	-1.93E-01	-4.71E-01
Thrombocythemia	3B63	Whole blood	6.56E-01	-4.00E-02	-1.72E-01
Thrombocytopenia	3B64	Whole blood	8.57E-01	1.03E-01	3.51E-01
Thyroid cancer	2D10	Thyroid	2.56E-30	4.82E-01	1.61E+00
Tibial muscular dystrophy	8C75	Muscle tissue	6.00E-01	-1.77E-01	-2.43E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	4.68E-03	6.77E-01	2.98E+00
Type 2 diabetes	5A11	Liver tissue	3.79E-02	4.70E-01	2.16E+00
Ureter cancer	2C92	Urothelium	8.48E-01	1.61E-02	8.66E-02
Uterine cancer	2C78	Endometrium tissue	1.58E-01	9.12E-02	1.78E-01
Vitiligo	ED63.0	Skin	8.66E-01	-2.07E-02	-7.99E-02