Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTHE530)

• DTP Name: Probable small intestine urate exporter (SLC17A4) DTP Info
• Gene Name: SLC17A4

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	9.89E-01	-1.47E-02	-1.09E-01
Adrenocortical carcinoma	2D11.Z	Kidney	5.98E-01	-3.84E-02	-1.38E-01
Alopecia	ED70	Skin from scalp	2.11E-02	6.67E-02	4.58E-01
Alzheimer's disease	8A20	Entorhinal cortex	8.94E-01	-9.82E-03	-6.82E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.33E-01	6.41E-02	4.49E-01
Aortic stenosis	BB70	Calcified aortic valve	8.18E-01	-8.43E-02	-1.15E-01
Apnea	7A40	Hyperplastic tonsil	6.37E-01	-1.33E-01	-4.77E-01
Arthropathy	FA00-FA5Z	Peripheral blood	8.26E-01	7.79E-03	7.50E-02
Asthma	CA23	Nasal and bronchial airway	6.69E-02	-6.30E-02	-1.92E-01
Atopic dermatitis	EA80	Skin	2.65E-02	-6.75E-03	-8.11E-02
Autism	6A02	Whole blood	1.04E-02	-9.82E-02	-6.60E-01
Autoimmune uveitis	9A96	Peripheral monocyte	5.89E-01	-1.72E-01	-2.33E+00
Autosomal dominant monocytopenia	4B04	Whole blood	2.05E-01	1.35E-01	1.12E+00
Bacterial infection of gingival	1C1H	Gingival tissue	3.52E-01	-7.20E-03	-2.67E-02
Batten disease	5C56.1	Whole blood	1.50E-01	8.08E-02	1.70E+00
Behcet's disease	4A62	Peripheral blood	9.89E-01	2.10E-02	1.05E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.10E-02	-3.16E-02	-2.16E-01
Bladder cancer	2C94	Bladder tissue	2.23E-07	8.03E-01	6.17E+00
Breast cancer	2C60-2C6Z	Breast tissue	7.22E-13	-7.98E-02	-2.60E-01
Cardioembolic stroke	8B11.20	Whole blood	8.84E-04	1.82E-01	1.06E+00
Cervical cancer	2C77	Cervical tissue	3.69E-01	-4.43E-02	-1.21E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	2.28E-01	5.70E-02	4.12E-01
Chronic hepatitis C	1E51.1	Whole blood	5.26E-01	1.15E-01	9.25E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	7.40E-02	1.70E-01	8.81E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	4.54E-01	1.64E-02	1.24E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	2.49E-01	1.02E-01	6.10E-01
Colon cancer	2B90	Colon tissue	7.09E-76	-1.81E+00	-3.01E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	4.88E-01	1.33E-02	1.64E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	1.31E-01	-6.64E-02	-8.59E-01
Endometriosis	GA10	Endometrium tissue	8.84E-03	1.79E-01	7.62E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.70E-01	-1.45E-02	-1.36E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.00E-02	-1.74E-01	-8.13E-01
Gastric cancer	2B72	Gastric tissue	9.51E-01	-2.29E-02	-1.18E-01
Glioblastopma	2A00.00	Nervous tissue	5.52E-01	-4.94E-02	-1.64E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.48E-03	-3.09E-01	-1.74E+00
Head and neck cancer	2D42	Head and neck tissue	1.66E-02	-3.27E-02	-2.28E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.29E-01	-2.80E-02	-8.75E-02
Huntington's disease	8A01.10	Whole blood	9.86E-01	1.47E-02	1.15E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	4.47E-01	-2.26E-02	-8.23E-02
Immunodeficiency	4A00-4A20	Peripheral blood	3.89E-03	1.40E-01	1.59E+00
Influenza	1.00E+30	Whole blood	2.24E-02	3.28E-01	2.82E+00
Interstitial cystitis	GC00.3	Bladder tissue	4.74E-01	-3.98E-02	-5.93E-01
Intracranial aneurysm	8B01.0	Intracranial artery	9.12E-02	5.44E-02	4.90E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	8.77E-01	-2.88E-02	-7.27E-02
Ischemic stroke	8B11	Peripheral blood	7.49E-03	1.02E-01	9.38E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	2.10E-03	4.95E-02	3.13E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	9.24E-01	2.50E-02	1.04E-01
Lateral sclerosis	8B60.4	Skin	5.46E-02	1.59E-01	1.53E+00
Liver cancer	2C12.0	Liver tissue	5.58E-03	3.17E-01	5.65E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.40E-02	-3.15E-01	-1.15E+00
Lung cancer	2C25	Lung tissue	2.40E-01	2.34E-02	1.44E-01
Lupus erythematosus	4A40	Whole blood	3.49E-02	-1.03E-01	-2.27E-01
Major depressive disorder	6A70-6A7Z	Whole blood	3.53E-01	2.63E-02	1.10E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	6.53E-01	2.03E-02	1.40E-01
Melanoma	2C30	Skin	6.62E-01	4.15E-02	6.43E-02
Multiple myeloma	2A83.1	Bone marrow	2.53E-05	-4.54E-01	-3.63E+00
Multiple myeloma	2A83.1	Peripheral blood	1.73E-01	1.53E-01	9.09E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.57E-01	5.92E-02	3.20E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.49E-01	3.96E-02	2.26E-01
Myelofibrosis	2A20.2	Whole blood	1.25E-02	1.24E-01	8.48E-01
Myocardial infarction	BA41-BA50	Peripheral blood	2.93E-01	1.29E-01	3.32E-01
Myopathy	8C70.6	Muscle tissue	2.90E-01	-1.88E-01	-1.01E+00
Neonatal sepsis	KA60	Whole blood	4.70E-01	-4.27E-02	-2.63E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.20E-04	-8.75E-01	-2.23E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.48E-01	-2.54E-01	-5.97E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	6.56E-02	1.12E-01	3.03E+00
Olive pollen allergy	CA08.00	Peripheral blood	3.97E-01	1.58E-01	1.07E+00
Oral cancer	2B6E	Oral tissue	1.03E-01	-4.04E-01	-1.22E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.71E-01	7.10E-02	4.64E-01
Osteoporosis	FB83.1	Bone marrow	7.08E-01	-8.74E-03	-1.30E-01
Ovarian cancer	2C73	Ovarian tissue	1.71E-01	-1.34E-01	-7.67E-01
Pancreatic cancer	2C10	Pancreas	2.65E-02	-8.21E-01	-1.30E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	1.90E-01	1.20E-01	9.20E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	8.92E-01	4.96E-02	5.98E-01
Pituitary cancer	2D12	Pituitary tissue	3.77E-01	-1.58E-01	-6.77E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	8.58E-01	-4.04E-02	-1.68E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	9.22E-01	-4.46E-02	-2.50E-01
Polycythemia vera	2A20.4	Whole blood	5.20E-08	1.75E-01	1.04E+00
Pompe disease	5C51.3	Biceps muscle	3.16E-01	-8.46E-02	-1.09E+00
Preterm birth	KA21.4Z	Myometrium	5.48E-01	3.52E-02	1.69E-01
Prostate cancer	2C82	Prostate	1.84E-04	-8.82E-01	-1.49E+00
Psoriasis	EA90	Skin	2.65E-15	-1.70E-01	-8.73E-01
Rectal cancer	2B92	Rectal colon tissue	1.68E-05	-8.87E-01	-4.08E+00
Renal cancer	2C90-2C91	Kidney	3.38E-05	3.00E-01	9.44E-01
Retinoblastoma	2D02.2	Uvea	1.59E-04	-3.20E-01	-3.31E+00
Rheumatoid arthritis	FA20	Synovial tissue	7.92E-01	1.59E-02	7.11E-02
Rhinovirus infection	CA42.1	Nasal epithelium tissue	8.33E-01	2.35E-02	2.01E-01
Schizophrenia	6A20	Prefrontal cortex	5.43E-01	7.84E-04	2.59E-03
Schizophrenia	6A20	Superior temporal cortex	4.27E-01	-7.71E-02	-7.53E-01
Scleroderma	4A42.Z	Whole blood	7.49E-01	-2.44E-02	-2.27E-01
Seizure	8A60-8A6Z	Whole blood	5.11E-01	-8.68E-02	-5.84E-01
Sensitive skin	EK0Z	Skin	2.41E-01	-9.04E-03	-1.00E-01
Sepsis with septic shock	1G41	Whole blood	1.68E-03	4.07E-02	2.07E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.19E-01	3.18E-01	1.08E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.88E-01	6.03E-02	4.54E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	5.32E-01	-1.59E-02	-1.92E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.11E-01	-1.08E-01	-1.55E+00
Skin cancer	2C30-2C3Z	Skin	5.71E-01	-9.06E-02	-2.68E-01
Thrombocythemia	3B63	Whole blood	1.24E-02	1.61E-02	1.03E-01
Thrombocytopenia	3B64	Whole blood	2.19E-01	9.95E-02	6.27E-01
Thyroid cancer	2D10	Thyroid	4.36E-01	1.94E-02	9.74E-02
Tibial muscular dystrophy	8C75	Muscle tissue	8.99E-01	-3.37E-02	-2.23E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.66E-02	1.88E-01	2.57E+00
Type 2 diabetes	5A11	Liver tissue	3.50E-01	-9.89E-02	-2.17E-01
Ureter cancer	2C92	Urothelium	5.73E-01	-1.17E-02	-1.03E-01
Uterine cancer	2C78	Endometrium tissue	4.06E-01	1.02E-01	2.84E-01
Vitiligo	ED63.0	Skin	3.89E-01	-1.55E-02	-2.20E-01