Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTJF3DX)

• DTP Name: L-type amino acid transporter 2 (SLC7A8) DTP Info
• Gene Name: LAT2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	4.05E-01	1.91E-02	8.44E-02
Adrenocortical carcinoma	2D11.Z	Kidney	3.74E-01	-1.91E-01	-3.56E-01
Alopecia	ED70	Skin from scalp	3.78E-06	-7.49E-01	-1.04E+00
Alzheimer's disease	8A20	Entorhinal cortex	3.71E-06	-3.04E-01	-5.26E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	6.03E-01	5.41E-02	5.03E-02
Aortic stenosis	BB70	Calcified aortic valve	1.85E-01	8.81E-02	1.48E-01
Apnea	7A40	Hyperplastic tonsil	4.23E-03	-6.21E-01	-1.96E+00
Arthropathy	FA00-FA5Z	Peripheral blood	1.40E-01	1.05E-01	5.58E-01
Asthma	CA23	Nasal and bronchial airway	8.37E-01	8.86E-02	1.42E-01
Atopic dermatitis	EA80	Skin	1.69E-01	-2.11E-01	-5.38E-01
Autism	6A02	Whole blood	8.89E-01	1.64E-02	4.78E-02
Autoimmune uveitis	9A96	Peripheral monocyte	3.54E-01	-6.20E-02	-5.63E-01
Autosomal dominant monocytopenia	4B04	Whole blood	3.63E-01	-1.17E-01	-6.72E-01
Bacterial infection of gingival	1C1H	Gingival tissue	5.62E-07	-4.87E-01	-7.97E-01
Batten disease	5C56.1	Whole blood	8.62E-01	6.23E-03	3.81E-02
Behcet's disease	4A62	Peripheral blood	3.17E-01	6.84E-02	2.99E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.04E-02	-1.05E-01	-5.43E-01
Bladder cancer	2C94	Bladder tissue	3.08E-02	-9.18E-01	-1.62E+00
Breast cancer	2C60-2C6Z	Breast tissue	4.20E-07	-5.82E-01	-7.69E-01
Cardioembolic stroke	8B11.20	Whole blood	2.82E-02	5.41E-02	2.29E-01
Cervical cancer	2C77	Cervical tissue	6.20E-01	8.46E-02	1.83E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.09E-01	3.18E-01	6.02E-01
Chronic hepatitis C	1E51.1	Whole blood	6.70E-01	3.68E-02	2.51E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.52E-02	2.75E-01	5.71E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	4.44E-01	1.42E-01	3.37E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	4.56E-01	4.99E-02	2.33E-01
Colon cancer	2B90	Colon tissue	1.99E-05	-3.74E-01	-6.23E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.47E-01	-4.29E-02	-2.08E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	3.70E-01	4.41E-02	2.60E-01
Endometriosis	GA10	Endometrium tissue	1.13E-01	4.47E-01	4.64E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.72E-01	8.78E-02	2.76E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.13E-01	-9.53E-02	-3.82E-01
Gastric cancer	2B72	Gastric tissue	3.75E-01	-4.87E-01	-3.19E-01
Glioblastopma	2A00.00	Nervous tissue	3.36E-19	-3.38E-01	-5.96E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	6.59E-01	-2.37E-01	-3.24E-01
Head and neck cancer	2D42	Head and neck tissue	6.69E-32	1.24E+00	4.02E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.45E-02	-3.95E-01	-8.95E-01
Huntington's disease	8A01.10	Whole blood	4.33E-01	5.04E-02	3.14E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	6.34E-02	-4.16E-01	-1.15E+00
Immunodeficiency	4A00-4A20	Peripheral blood	9.49E-02	-1.03E-01	-3.76E-01
Influenza	1.00E+30	Whole blood	7.29E-03	4.78E-01	4.54E+00
Interstitial cystitis	GC00.3	Bladder tissue	8.17E-04	-1.26E+00	-3.12E+00
Intracranial aneurysm	8B01.0	Intracranial artery	9.67E-01	1.29E-02	4.14E-02
Irritable bowel syndrome	DD91.0	Rectal colon tissue	9.48E-01	4.27E-02	1.04E-01
Ischemic stroke	8B11	Peripheral blood	9.09E-02	1.23E-01	5.80E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	5.89E-02	7.03E-02	2.31E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	2.47E-01	1.26E-01	4.37E-01
Lateral sclerosis	8B60.4	Skin	8.23E-01	-2.93E-01	-6.94E-01
Liver cancer	2C12.0	Liver tissue	1.50E-03	-3.84E-01	-8.41E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.99E-06	1.34E+00	4.50E+00
Lung cancer	2C25	Lung tissue	3.77E-01	-2.90E-01	-3.81E-01
Lupus erythematosus	4A40	Whole blood	9.21E-06	-1.89E-01	-4.07E-01
Major depressive disorder	6A70-6A7Z	Whole blood	9.36E-01	-3.82E-02	-1.11E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	2.61E-01	-5.79E-02	-3.11E-01
Melanoma	2C30	Skin	4.68E-01	8.45E-01	5.34E-01
Multiple myeloma	2A83.1	Bone marrow	3.30E-05	-6.62E-01	-3.66E+00
Multiple myeloma	2A83.1	Peripheral blood	1.32E-01	1.76E-01	9.74E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.32E-02	3.15E-01	1.87E+00
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	3.10E-04	2.70E-01	6.87E-01
Myelofibrosis	2A20.2	Whole blood	2.57E-02	9.35E-02	4.57E-01
Myocardial infarction	BA41-BA50	Peripheral blood	4.22E-01	3.88E-02	1.14E-01
Myopathy	8C70.6	Muscle tissue	2.51E-02	-2.44E-01	-1.06E+00
Neonatal sepsis	KA60	Whole blood	8.99E-02	-5.67E-02	-1.94E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.10E-06	-1.17E+00	-3.31E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.26E-01	2.59E-01	7.27E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.25E-02	-3.50E-01	-1.28E+00
Olive pollen allergy	CA08.00	Peripheral blood	1.01E-01	1.08E+00	1.57E+00
Oral cancer	2B6E	Oral tissue	3.56E-13	1.05E+00	2.14E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	6.97E-01	1.65E-02	2.51E-02
Osteoporosis	FB83.1	Bone marrow	5.49E-01	-2.66E-01	-6.11E-01
Ovarian cancer	2C73	Ovarian tissue	3.78E-01	-2.66E-01	-2.24E-01
Pancreatic cancer	2C10	Pancreas	4.65E-01	-5.95E-02	-7.26E-02
Parkinson's disease	8A00.0	Substantia nigra tissue	7.23E-02	-2.92E-01	-4.31E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	5.51E-01	-2.56E-02	-1.29E-01
Pituitary cancer	2D12	Pituitary tissue	4.13E-01	-3.28E-01	-2.89E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	3.07E-02	-3.64E-01	-4.12E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	1.33E-01	-1.03E-01	-8.27E-01
Polycythemia vera	2A20.4	Whole blood	2.22E-01	2.41E-02	1.26E-01
Pompe disease	5C51.3	Biceps muscle	3.73E-01	8.80E-02	3.15E-01
Preterm birth	KA21.4Z	Myometrium	4.11E-01	-4.02E-02	-3.55E-02
Prostate cancer	2C82	Prostate	8.02E-01	2.04E-01	1.89E-01
Psoriasis	EA90	Skin	4.49E-03	3.05E-01	4.30E-01
Rectal cancer	2B92	Rectal colon tissue	5.65E-02	3.31E-01	1.42E+00
Renal cancer	2C90-2C91	Kidney	1.46E-04	-2.31E+00	-2.27E+00
Retinoblastoma	2D02.2	Uvea	2.07E-01	4.78E-01	1.45E+00
Rheumatoid arthritis	FA20	Synovial tissue	5.98E-02	1.02E-01	1.61E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	2.48E-02	1.76E-01	7.03E-01
Schizophrenia	6A20	Prefrontal cortex	4.48E-01	2.11E-03	2.81E-03
Schizophrenia	6A20	Superior temporal cortex	2.41E-01	-8.64E-02	-3.55E-01
Scleroderma	4A42.Z	Whole blood	6.75E-01	-8.01E-02	-3.12E-01
Seizure	8A60-8A6Z	Whole blood	5.17E-01	-4.17E-02	-2.08E-01
Sensitive skin	EK0Z	Skin	2.87E-01	2.15E-01	5.54E-01
Sepsis with septic shock	1G41	Whole blood	1.14E-02	-1.23E-01	-4.56E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.83E-01	2.31E-01	8.65E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	2.74E-01	3.28E-02	1.45E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.26E-01	2.89E-01	8.37E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.19E-01	1.06E+00	2.02E+00
Skin cancer	2C30-2C3Z	Skin	2.38E-01	-4.16E-02	-5.97E-02
Thrombocythemia	3B63	Whole blood	4.79E-01	1.24E-02	6.29E-02
Thrombocytopenia	3B64	Whole blood	1.82E-01	4.65E-03	2.98E-03
Thyroid cancer	2D10	Thyroid	2.30E-05	-5.15E-01	-6.59E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.13E-02	4.02E-01	1.06E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.17E-02	-4.34E-01	-2.48E+00
Type 2 diabetes	5A11	Liver tissue	7.29E-01	-2.63E-02	-6.17E-02
Ureter cancer	2C92	Urothelium	3.21E-01	1.47E-04	7.56E-04
Uterine cancer	2C78	Endometrium tissue	8.37E-01	-8.30E-02	-8.53E-02
Vitiligo	ED63.0	Skin	4.60E-01	3.61E-02	6.16E-02