Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTWLACT)

• DTP Name: Vesicular H(+)/Aspartate-glutamate cotransporter (SLC17A5) DTP Info
• Gene Name: AST

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	9.10E-12	-3.56E-01	-9.31E-01
Adrenocortical carcinoma	2D11.Z	Kidney	2.33E-04	4.13E-01	1.05E+00
Alopecia	ED70	Skin from scalp	3.22E-01	9.75E-02	2.61E-01
Alzheimer's disease	8A20	Entorhinal cortex	3.28E-02	-8.91E-02	-3.73E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.17E-01	1.00E-01	4.27E-01
Aortic stenosis	BB70	Calcified aortic valve	6.36E-01	1.98E-01	7.06E-01
Apnea	7A40	Hyperplastic tonsil	3.70E-01	-1.29E-01	-7.74E-01
Arthropathy	FA00-FA5Z	Peripheral blood	6.86E-01	1.53E-03	1.08E-02
Asthma	CA23	Nasal and bronchial airway	8.14E-03	1.29E-01	2.37E-01
Atopic dermatitis	EA80	Skin	5.19E-04	-2.99E-01	-1.42E+00
Autism	6A02	Whole blood	3.39E-01	-4.96E-02	-2.44E-01
Autoimmune uveitis	9A96	Peripheral monocyte	4.45E-02	5.99E-01	1.75E+00
Autosomal dominant monocytopenia	4B04	Whole blood	1.62E-01	4.06E-01	1.23E+00
Bacterial infection of gingival	1C1H	Gingival tissue	1.89E-11	2.73E-01	1.04E+00
Batten disease	5C56.1	Whole blood	6.21E-01	1.35E-01	4.26E-01
Behcet's disease	4A62	Peripheral blood	9.36E-01	-1.20E-02	-3.79E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.52E-01	-1.16E-02	-6.11E-02
Bladder cancer	2C94	Bladder tissue	2.28E-02	-5.40E-01	-1.47E+00
Breast cancer	2C60-2C6Z	Breast tissue	4.66E-05	-1.66E-01	-4.42E-01
Cardioembolic stroke	8B11.20	Whole blood	7.33E-07	4.79E-01	1.59E+00
Cervical cancer	2C77	Cervical tissue	4.84E-01	-7.93E-02	-2.74E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	8.21E-01	-6.85E-02	-2.34E-01
Chronic hepatitis C	1E51.1	Whole blood	7.74E-01	1.13E-01	4.05E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	3.28E-01	-1.50E-01	-5.18E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.25E-01	1.34E-01	3.66E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	5.62E-02	3.38E-01	1.32E+00
Colon cancer	2B90	Colon tissue	8.99E-73	-8.73E-01	-2.42E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.79E-01	7.84E-02	3.77E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	7.73E-01	-1.00E-01	-1.81E-01
Endometriosis	GA10	Endometrium tissue	3.72E-01	-2.39E-01	-2.66E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.31E-01	-6.77E-02	-3.35E-01
Familial hypercholesterolemia	5C80.00	Whole blood	6.50E-03	1.45E-01	6.21E-01
Gastric cancer	2B72	Gastric tissue	1.60E-01	4.71E-01	8.40E-01
Glioblastopma	2A00.00	Nervous tissue	2.90E-42	-3.24E-01	-9.47E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	3.48E-01	2.23E-01	4.87E-01
Head and neck cancer	2D42	Head and neck tissue	3.73E-13	-5.63E-01	-1.21E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	7.52E-01	2.53E-02	7.58E-02
Huntington's disease	8A01.10	Whole blood	7.27E-01	-5.35E-02	-1.73E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	9.06E-01	2.13E-02	1.27E-01
Immunodeficiency	4A00-4A20	Peripheral blood	2.87E-01	-2.26E-02	-3.92E-01
Influenza	1.00E+30	Whole blood	7.01E-02	-8.35E-01	-7.43E+00
Interstitial cystitis	GC00.3	Bladder tissue	7.52E-03	-3.62E-01	-1.80E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.92E-05	5.23E-01	1.71E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.66E-01	-1.09E-01	-2.75E-01
Ischemic stroke	8B11	Peripheral blood	3.52E-01	-2.71E-01	-6.24E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.69E-04	2.11E-01	3.97E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	2.76E-01	-1.94E-01	-3.88E-01
Lateral sclerosis	8B60.4	Skin	1.06E-01	-2.49E-01	-6.20E+00
Liver cancer	2C12.0	Liver tissue	5.33E-05	2.99E-01	7.49E-01
Liver failure	DB99.7-DB99.8	Liver tissue	6.98E-03	-3.13E-01	-1.15E+00
Lung cancer	2C25	Lung tissue	1.40E-34	-4.17E-01	-1.18E+00
Lupus erythematosus	4A40	Whole blood	3.50E-01	1.61E-01	2.87E-01
Major depressive disorder	6A70-6A7Z	Whole blood	3.95E-01	5.03E-02	6.73E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	2.23E-01	4.23E-02	2.59E-01
Melanoma	2C30	Skin	8.79E-01	2.24E-01	2.06E-01
Multiple myeloma	2A83.1	Bone marrow	3.50E-01	4.87E-02	2.20E-01
Multiple myeloma	2A83.1	Peripheral blood	1.64E-01	7.25E-02	4.26E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.02E-02	-3.00E-01	-1.13E+00
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	1.42E-05	3.38E-01	1.07E+00
Myelofibrosis	2A20.2	Whole blood	6.17E-02	9.08E-02	9.14E-01
Myocardial infarction	BA41-BA50	Peripheral blood	9.66E-05	-3.98E-01	-7.25E-01
Myopathy	8C70.6	Muscle tissue	1.40E-02	4.30E-01	1.18E+00
Neonatal sepsis	KA60	Whole blood	1.06E-18	5.25E-01	1.89E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	5.00E-04	-8.68E-01	-2.01E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	3.66E-01	2.13E-01	6.28E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.96E-01	-3.13E-02	-1.21E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.69E-01	3.03E-01	8.42E-01
Oral cancer	2B6E	Oral tissue	5.42E-01	1.08E-01	1.29E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	1.68E-01	3.69E-01	4.20E-01
Osteoporosis	FB83.1	Bone marrow	5.61E-01	1.37E-01	4.49E-01
Ovarian cancer	2C73	Ovarian tissue	2.16E-04	8.47E-01	1.90E+00
Pancreatic cancer	2C10	Pancreas	6.82E-07	6.41E-01	1.79E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	9.19E-01	-1.30E-02	-2.10E-02
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.74E-05	3.22E-01	1.49E+00
Pituitary cancer	2D12	Pituitary tissue	5.43E-01	-2.88E-01	-1.12E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.05E-04	-5.02E-01	-1.95E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	5.08E-01	7.70E-02	5.30E-01
Polycythemia vera	2A20.4	Whole blood	8.11E-06	1.25E-01	1.03E+00
Pompe disease	5C51.3	Biceps muscle	9.05E-01	2.40E-01	8.81E-01
Preterm birth	KA21.4Z	Myometrium	4.77E-01	1.25E-01	3.14E-01
Prostate cancer	2C82	Prostate	6.73E-01	-1.42E-01	-1.96E-01
Psoriasis	EA90	Skin	1.63E-23	-6.74E-01	-1.64E+00
Rectal cancer	2B92	Rectal colon tissue	5.76E-04	-8.82E-01	-2.33E+00
Renal cancer	2C90-2C91	Kidney	4.59E-01	-4.94E-02	-8.12E-02
Retinoblastoma	2D02.2	Uvea	3.41E-05	-9.59E-01	-2.74E+00
Rheumatoid arthritis	FA20	Synovial tissue	9.35E-03	7.64E-01	9.75E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	7.64E-01	1.60E-02	7.35E-02
Schizophrenia	6A20	Prefrontal cortex	2.33E-02	-1.08E-01	-3.68E-01
Schizophrenia	6A20	Superior temporal cortex	6.95E-01	-5.94E-02	-3.11E-01
Scleroderma	4A42.Z	Whole blood	5.90E-01	6.36E-03	4.81E-02
Seizure	8A60-8A6Z	Whole blood	8.54E-01	-1.46E-01	-3.97E-01
Sensitive skin	EK0Z	Skin	4.61E-01	-1.79E-04	-1.07E-03
Sepsis with septic shock	1G41	Whole blood	1.78E-71	4.46E-01	2.30E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.50E-01	1.50E-01	7.28E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	7.19E-03	4.05E-01	1.07E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.72E-01	6.59E-02	1.63E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.41E-01	-1.39E-01	-3.44E-01
Skin cancer	2C30-2C3Z	Skin	3.34E-01	1.83E-02	4.14E-02
Thrombocythemia	3B63	Whole blood	3.83E-03	7.66E-02	7.73E-01
Thrombocytopenia	3B64	Whole blood	1.31E-01	-5.01E-01	-6.66E-01
Thyroid cancer	2D10	Thyroid	9.26E-13	9.08E-01	1.83E+00
Tibial muscular dystrophy	8C75	Muscle tissue	1.04E-06	6.33E-01	2.09E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.96E-03	-3.03E-01	-3.99E+00
Type 2 diabetes	5A11	Liver tissue	2.20E-01	2.54E-01	8.43E-01
Ureter cancer	2C92	Urothelium	6.37E-01	-2.97E-02	-1.52E-01
Uterine cancer	2C78	Endometrium tissue	1.85E-06	-2.89E-01	-6.51E-01
Vitiligo	ED63.0	Skin	9.90E-01	-9.35E-02	-5.45E-01