Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DE6SOC5)

• DME Name: Copper amine oxidase (AOC3) DME Info
• Gene Name: AOC3

Molecule-Related Drug & Molecule List

1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tresperimus	DMOVBSF	Autoimmune diabetes	5A10	Discontinued in Phase 3	[1]

4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Benzylamine	DMRM6ES	N. A.	N. A.	Investigative	[2]
Methylamine	DMTPL4W	N. A.	N. A.	Investigative	[2]
PHENETHYLAMINE	DMX0G4F	Discovery agent	N.A.	Investigative	[2]
tyramine	DM4UXT1	Discovery agent	N.A.	Investigative	[2]

References

• [1] Metabolism of tresperimus by rat aorta semicarbazide-sensitive amine oxidase (SSAO). Fundam Clin Pharmacol. 2002 Dec;16(6):461-70.
• [2] The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase. Cell Mol Life Sci. 2009 Aug;66(16):2743-57.