Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DEKZQY6)

DME Name	Dipeptidyl peptidase IV (DPP4) DME Info
Gene Name	DPP4

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

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3 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Exenatide	DMYHBKN	Inflammation	1A00-CA43.1	Approved	[1]
Liraglutide	DM3FXPS	Non-insulin dependent diabetes	5A11	Approved	[2]
Semaglutide	DMAGFOD	Type-2 diabetes	5A11	Approved	[3]
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Molecule Interaction Atlas

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References

1	In vitro metabolic stability of exendin-4: pharmacokinetics and identification of cleavage products. PLoS One. 2015 Feb 27;10(2):e0116805.
2	Metabolism and excretion of the once-daily human glucagon-like peptide-1 analog liraglutide in healthy male subjects and its in vitro degradation by dipeptidyl peptidase IV and neutral endopeptidase. Drug Metab Dispos. 2010 Nov;38(11):1944-53.
3	Absorption, metabolism and excretion of the GLP-1 analogue semaglutide in humans and nonclinical species. Eur J Pharm Sci. 2017 Jun 15;104:31-41.