Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DELAPDY)

• DME Name: Nitroreductase (NTR) DME Info
• Gene Name: nfrA2

Molecule-Related Drug & Molecule List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Metronidazole	DMTIVEN	Abscess		Approved	[1], [2]

References

• [1] Isolation of metronidazole-resistant Bacteroides fragilis carrying the nimA nitroreductase gene from a patient in Washington State. J Clin Microbiol. 2004 Sep;42(9):4127-9. Case Reports
• [2] Biotransformation of 1-nitropyrene in intestinal anaerobic bacteria. Microbiol Immunol. 1982;26(11):993-1005.