Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DER6XYF)

DME Name	Tryptophan 5-hydroxylase 2 (TPH2) DME Info
Gene Name	TPH2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Investigative Drug(s)

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2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
L-Tryptophan	DMIBH7M	Depression	6A70-6A7Z	Approved	[1]
Tetrahydrobiopterin	DMINZ4W	Malnutrition	5B50-5B71	Approved	[2]
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1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sapropterin	DM6GE21	Phenylketonuria	5C50.0	Investigative	[2]
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Molecule Interaction Atlas

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References

1	Strain differences in basal and post-citalopram extracellular 5-HT in the mouse medial prefrontal cortex and dorsal hippocampus: relation with tryptophan hydroxylase-2 activity. J Neurochem. 2007 Nov;103(3):1111-20.
2	Characterization of wild-type and mutant forms of human tryptophan hydroxylase 2. J Neurochem. 2007 Mar;100(6):1648-57.