Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DEWYTJB)

• DME Name: Aldehyde dehydrogenase 2 (ALDH2) DME Info
• Gene Name: ALDH2

Molecule-Related Drug & Molecule List

5 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Amyl nitrite	DMJKO05	Angina pectoris	BA40	Approved	[1]
Benzyl alcohol	DMBVYDI	Head and body lice	1G00.0	Approved	[2]
Paraldehyde	DMOC1BX	Insomnia	7A00-7A0Z	Approved	[3]
Pentaerythritol tetranitrate	DMZ9MO5	Angina pectoris	BA40	Approved	[4]
SILODOSIN	DMJSBT6	Benign prostatic hyperplasia	GA90	Approved	[5]

References

• [1] Mitochondrial aldehyde dehydrogenase mediates vasodilator responses of glyceryl trinitrate and sodium nitrite in the pulmonary vascular bed of the rat. Am J Physiol Heart Circ Physiol. 2010 Sep;299(3):H819-26.
• [2] Effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on toluene metabolism in humans. Toxicol Appl Pharmacol. 1995 Aug;133(2):295-304.
• [3] Paraldehyde. J Appl Toxicol. 1991 Oct;11(5):379-81.
• [4] OSHA Occupational Chemical Database: drug information.
• [5] Pharmacokinetics and disposition of silodosin (KMD-3213). Yakugaku Zasshi. 2006 Mar;126 Spec no.:237-45.