Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTP (ID: DT7JELC)

DTP Name	Apical sodium-dependent bile acid transporter (SLC10A2) DTP Info
UniProt ID	NTCP2_HUMAN
Gene Name	ASBT

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

Approved Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cholic acid	DM7OKQV	Peroxisomal disorder	5C57	Approved	[1]
Deoxycholic acid	DM3GYAL	N. A.	N. A.	Approved	[2]
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2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sodium taurocholate	DM3GO0J	Type-2 diabetes	5A11	Phase 1/2	[3]
Taurocholic acid	DM2LZ8F	Type-2 diabetes	5A11	Phase 1/2	[3]
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1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Glycodeoxycholic acid	DM1XEJV	Discovery agent	N.A.	Investigative	[1]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter. Am J Physiol. 1998 Jan;274(1):G157-69.
2	Functional nanoparticles exploit the bile acid pathway to overcome multiple barriers of the intestinal epithelium for oral insulin delivery. Biomaterials. 2018 Jan;151:13-23.
3	Identification of a region of the ileal-type sodium/bile acid cotransporter interacting with a competitive bile acid transport inhibitor. Biochemistry. 2002 Dec 17;41(50):14916-24.