Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT28ZON)

DTT Name	H-ras messenger RNA (HRAS mRNA) DTT Info
Gene Name	HRAS

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Discontinued Drug(s)

Investigative Drug(s)

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1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 2503	DMEMKIS	N. A.	N. A.	Discontinued in Phase 2	[1]
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3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 13920	DM4PM1G	Solid tumour/cancer	2A00-2F9Z	Investigative	[2]
ISIS 2502	DMYTXBS	Discovery agent	N.A.	Investigative	[3]
ISIS 6186	DMH7LPO	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	A phase I trial of ISIS 2503, an antisense inhibitor of H-ras, in combination with gemcitabine in patients with advanced cancer. Clin Cancer Res. 2003 Jan;9(1):115-23.
2	US patent application no. 7,425,545, Modulation of C-reactive protein expression.
3	US patent application no. 5,965,722, Antisense inhibition of ras gene with chimeric and alternating oligonucleotides.