Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT30NW6)

DTT Name	Chloride channel protein 2 (CLC-2) DTT Info
Gene Name	CLCN2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Lubiprostone	DMJTEMW	Chronic idiopathic constipation	DC32	Approved	[1]
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1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
RK-023	DM2VO97	Alopecia	ED70	Phase 2	[2]
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3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acid-activated omeprazole	DMTOEJX	Discovery agent	N.A.	Investigative	[3]
diphenylamine-2-carboxylic acid	DMBV19T	Discovery agent	N.A.	Investigative	[4]
NPPB	DMFIWAN	Discovery agent	N.A.	Investigative	[4]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Lubiprostone stimulates secretion from tracheal submucosal glands of sheep, pigs, and humans. Am J Physiol Lung Cell Mol Physiol. 2009 May;296(5):L811-24.
2	Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
3	ClC-2 Cl- channels in human lung epithelia: activation by arachidonic acid, amidation, and acid-activated omeprazole. Am J Physiol Cell Physiol. 2001 Jul;281(1):C46-54.
4	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 699).