Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT3C80U)

• DTT Name: T-cell-specific kinase (ITK) DTT Info
• Gene Name: ITK

Molecule-Related Drug & Molecule List

2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
JTE-051	DM2LBHN	Plaque psoriasis	EA90.0	Phase 2	[1]
CPI-818	DMMBQ20	T-cell lymphoma	2A90	Phase 1	[2]

2 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID27774824-Compound-Figure3Example7	DMXDOGK	N. A.	N. A.	Patented	[3]
Pyrazolo[4,3-c]pyridine derivative 2	DMCDFLQ	N. A.	N. A.	Patented	[3]

2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BMS-488516	DM6Y1QF	Inflammation	1A00-CA43.1	Investigative	[4]
BMS-509744	DMGH1LX	Inflammation	1A00-CA43.1	Investigative	[4]

References

• [1] Characterisation of a K390R ITK Kinase Dead Transgenic Mouse - Implications for ITK as a Therapeutic Target. PLoS One. 2014; 9(9): e107490.
• [2] Clinical pipeline report, company report or official report of Corvus Pharmaceuticals.
• [3] Inhibitors of JAK-family kinases: an update on the patent literature 2013-2015, part 1.Expert Opin Ther Pat. 2017 Feb;27(2):127-143.
• [4] Treatment of depersonalization with serotonin reuptake blockers. J Clin Psychopharmacol. 1990 Jun;10(3):200-3.