Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT4UGTF)

• DTT Name: Stromal cell-derived factor 1 (CXCL12) DTT Info
• Gene Name: CXCL12

Molecule-Related Drug & Molecule List

5 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dociparstat sodium	DMQLSMB	Acute myeloid leukaemia	2A60	Phase 3	[1]
MyoCell SDF-1	DMS9GE1	Heart failure	BD10-BD13	Phase 3	[2]
SDF-1	DM80HOV	Heart failure	BD10-BD13	Phase 2	[3]
NOX-A12	DMMKN4Q	Macular degeneration	9B78.3	Phase 1	[4]
REC-02	DMHT5XV	Congestive heart failure	BD10	Phase 1	[5]

References

• [1] Clinical pipeline report, company report or official report of Chimerix.
• [2] Stromal cell-derived factor-1 (SDF-1): homing factor for engineered regenerative medicine. Expert Opin Biol Ther. 2011 Feb;11(2):189-97.
• [3] SDF-1 in myocardial repair. Gene Ther. 2012 Jun;19(6):583-7.
• [4] SDF-1/CXCR4/CXCR7 is pivotal for vascular smooth muscle cell proliferation and chronic allograft vasculopathy. Transpl Int. 2015 Dec;28(12):1426-35.
• [5] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)