Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT58ZYW)

• DTT Name: Mycobacterium Isocitrate lyase (MycB icl) DTT Info
• Gene Name: MycB icl

Molecule-Related Drug & Molecule List

9 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2,2',3-Tribromo-4,4',5,5'-tetrahydroxybibenzyl	DMG7EPF	Discovery agent	N.A.	Investigative	[1]
3-bromopyruvate	DMYL3ST	Discovery agent	N.A.	Investigative	[2]
3-nitropropionate	DMH798G	Discovery agent	N.A.	Investigative	[2]
5,5'-methylenebis(3,4-dibromobenzene-1,2-diol)	DMZ693W	Discovery agent	N.A.	Investigative	[1]
Bis(2,3-dibromo-4,5-dihydroxyphenyl)ether	DMQ7KR1	Discovery agent	N.A.	Investigative	[1]
Bis(3-bromo-4,5-dihydroxyphenyl)methanone	DMUN50H	Discovery agent	N.A.	Investigative	[1]
Glyoxalate, Glyoxylate	DMQUP7O	Discovery agent	N.A.	Investigative	[3]
Halisulfate 1	DMJB87Q	Discovery agent	N.A.	Investigative	[4]
Hydrohalisulfate 1	DM0HQF6	Discovery agent	N.A.	Investigative	[4]

References

• [1] Bromophenols as Candida albicans isocitrate lyase inhibitors. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6644-8.
• [2] Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis. Nat Struct Biol. 2000 Aug;7(8):663-8.
• [3] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [4] Sesterterpene sulfates as isocitrate lyase inhibitors from tropical sponge Hippospongia sp. Bioorg Med Chem Lett. 2007 May 1;17(9):2483-6.