Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT5KIO9)

DTT Name	Ornithine transcarbamylase (OTC) DTT Info
Gene Name	OTC

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

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3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Avalotcagene ontaparvovec	DMAOHT4	Ornithine transcarbamylase deficiency	5C50.AY	Phase 3	[1]
ARCT-810	DM91F9I	Ornithine transcarbamylase deficiency	5C50.AY	Phase 2	[2]
DTX301	DM8M71U	Ornithine transcarbamylase deficiency	5C50.AY	Phase 1/2	[3]
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Molecule Interaction Atlas

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References

1	Prednisolone reduces the interferon response to AAV in cynomolgus macaques and may increase liver gene expression. Mol Ther Methods Clin Dev. 2022 Jan 19;24:292-305.
2	Clinical pipeline report, company report or official report of Arcturus Therapeutics
3	Clinical pipeline report, company report or official report of Ultragenyx Pharmaceutical.