Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT7ALZG)

• DTT Name: Integrin-linked protein kinase 1 (ILK) DTT Info
• Gene Name: ILK

Molecule-Related Drug & Molecule List

3 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US8754233, (4-Benzothiazol-2-yl-1H-pyrazol-3-yl)-[2-(1H-imidazol-4-yl)-ethyl]-amine	DMSYD3X	N. A.	N. A.	Patented	[1]
US8754233, 2-(3-Amino-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-6-sulfonic acid amide	DMJPQNH	N. A.	N. A.	Patented	[1]
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-(2-fluoro-phenyl)-2H-pyrazol-3-ylamine	DMJY0CD	N. A.	N. A.	Patented	[1]

2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
MST-400	DMUKWJ2	Solid tumour/cancer	2A00-2F9Z	Investigative	[2]
PMID21823616C22	DMXF32O	Discovery agent	N.A.	Investigative	[3]

References

• [1] Pyrazolylbenzothiazole derivatives and their use as therapeutic agents. US8754233.
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2041).
• [3] Identification and characterization of a novel integrin-linked kinase inhibitor. J Med Chem. 2011 Sep 22;54(18):6364-74.