Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT866WZ)

DTT Name	Angiotensinogen messenger RNA (AGT mRNA) DTT Info
Gene Name	AGT

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ION904	DMJUJT2	Hypertension	BA00-BA04	Phase 2	[1]
Zilebesiran	DMS2QRT	Hypertension	BA00-BA04	Phase 2	[2]
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Molecule Interaction Atlas

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References

1	Antisense oligonucleotides targeting hepatic angiotensinogen reduce atherosclerosis and liver steatosis in hypercholesterolemic mice. Glob Transl Med. 2023;2(1):288.
2	ClinicalTrials.gov (NCT05103332) A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Zilebesiran Used as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication. U.S.National Institutes of Health.