Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT94HRF)

DTT Name	Voltage-gated calcium channel alpha Cav1.1 (CACNA1S) DTT Info
Gene Name	CACNA1S

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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6 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(-)-(S)-BayK8644	DMEA9KH	Discovery agent	N.A.	Investigative	[1]
FPL64176	DMB8U4F	Discovery agent	N.A.	Investigative	[1]
SZ(+)-(S)-202-791	DM8L6ZF	Discovery agent	N.A.	Investigative	[1]
[3H](+)-cis-diltiazem	DMP6XL9	Discovery agent	N.A.	Investigative	[2]
[3H](+)-isradipine	DM7QE1J	Discovery agent	N.A.	Investigative	[3]
[3H](-)devapamil	DM0KGHP	Discovery agent	N.A.	Investigative	[4]
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⏷ Show the Full List of 6 Investigative Drug(s)

Molecule Interaction Atlas

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 528).
2	High-affinity binding of DTZ323, a novel derivative of diltiazem, to rabbit skeletal muscle L-type Ca++ channels. J Pharmacol Exp Ther. 1997 Apr;281(1):173-9.
3	Biochemical characterization of plasma membrane isolated from human skeletal muscle. FEBS Lett. 1985 Sep 2;188(2):222-6.
4	(-)-[3H]Desmethoxyverapamil, a novel Ca2+ channel probe. Binding characteristics and target size analysis of its receptor in skeletal muscle. FEBS Lett. 1984 Oct 29;176(2):371-7.