Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT9EQUY)

• DTT Name: Melanoma-associated antigen 4 (MAGEA4) DTT Info
• Gene Name: MAGEA4

Molecule-Related Drug & Molecule List

3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ADP-A2M4	DMRYH3M	Synovial sarcoma	2B5A	Phase 2	[1]
Afamitresgene autoleucel	DM1GR4M	Soft tissue sarcoma	2B57	Phase 2	[2]
CAR-T cells targeting MAGE-A4	DMUBEX4	Lung cancer	2C25.0	Phase 1/2	[3]

References

• [1] Clinical pipeline report, company report or official report of Adaptimmune.
• [2] Autologous T cell therapy for MAGE-A4(+) solid cancers in HLA-A*02(+) patients: a phase 1 trial. Nat Med. 2023 Jan;29(1):104-114.
• [3] ClinicalTrials.gov (NCT03356808) Antigen-specific T Cells Against Lung Cancer