Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT9PB26)

• DTT Name: Presynaptic density protein 95 (DLG4) DTT Info
• Gene Name: DLG4

Molecule-Related Drug & Molecule List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tat-NR2B9c	DMD6AUX	Cerebrovascular ischaemia	8B1Z	Phase 3	[1]

18 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-Methyl-2,4-Pentanediol	DMD45CU	Discovery agent	N.A.	Investigative	[2]
FETAV	DMO1N2T	Discovery agent	N.A.	Investigative	[3]
Guanosine-5'-Monophosphate	DM3SLZK	Discovery agent	N.A.	Investigative	[2]
KSG-LDTKNYKQTSV	DM5DTMQ	Discovery agent	N.A.	Investigative	[3]
KSG-YEKLSSIESDV	DMPLFRC	Discovery agent	N.A.	Investigative	[3]
N-(3,4-Dichlorophenyl)propyl-ETAV	DMTERF6	Discovery agent	N.A.	Investigative	[3]
N-(3,4-Difluorophenyl)propyl-ETAV	DMF2D4O	Discovery agent	N.A.	Investigative	[3]
N-(Naphthalene-2-yl)ethyl-ETAV	DMG8KXR	Discovery agent	N.A.	Investigative	[3]
N-Benzyl-ETAV	DMNPS4R	Discovery agent	N.A.	Investigative	[3]
N-Butyl-ETAV	DMY3HEF	Discovery agent	N.A.	Investigative	[3]
N-Cyclohexylethyl-ETAV	DMCH5M1	Discovery agent	N.A.	Investigative	[3]
N-Cyclohexylmethyl-ETAV	DMIC8Z6	Discovery agent	N.A.	Investigative	[3]
N-Ethyl-ETAV	DMPTNI8	Discovery agent	N.A.	Investigative	[3]
N-Methyl-ETAV	DMP1EF6	Discovery agent	N.A.	Investigative	[3]
N-Phenylethyl-ETAV	DM1VSO9	Discovery agent	N.A.	Investigative	[3]
N-Phenylpropyl-ETAV	DM90GNC	Discovery agent	N.A.	Investigative	[3]
N-Propyl-ETAV	DMUTDNV	Discovery agent	N.A.	Investigative	[3]
YGRKKRRQRRR-KLSSIESDV	DMV89B4	Discovery agent	N.A.	Investigative	[3]

References

• [1] Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain. Nature. 2012 Feb 29;483(7388):213-7.
• [2] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [3] Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. J Med Chem. 2008 Oct 23;51(20):6450-9.