General Information of DTT (ID: TT9PBIL)

DTT Name Glutamyl aminopeptidase (ENPEP) DTT Info
Gene Name ENPEP

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
1 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
QGC-001 DMAFUHK Hypertension BA00-BA04 Phase 2 [1]
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3 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
EC33 DM67549 Discovery agent N.A. Investigative [2]
KELATORPHAN DMOX8FD Discovery agent N.A. Investigative [3]
PMID10602705C40 DMLH73O Discovery agent N.A. Investigative [4]
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Molecule Interaction Atlas

References

1 Clinical pipeline report, company report or official report of Quantum Genomics.
2 Aminopeptidase A, which generates one of the main effector peptides of the brain renin-angiotensin system, angiotensin III, has a key role in central control of arterial blood pressure. Biochem Soc Trans. 2000;28(4):435-40.
3 Retro-inverso concept applied to the complete inhibitors of enkephalin-degrading enzymes. J Med Chem. 1988 Sep;31(9):1825-31.
4 Investigation of subsite preferences in aminopeptidase A (EC 3.4.11.7) led to the design of the first highly potent and selective inhibitors of this enzyme. J Med Chem. 1999 Dec 16;42(25):5197-211.