Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT9WOBN)

DTT Name	Cardiac myosin (MYBPC3) DTT Info
Gene Name	MYBPC3

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

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2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aficamten	DMJL09Z	Hypertrophic cardiomyopathy	BC43.1	Phase 3	[1]
Omecamtiv mecarbil	DM624TW	Heart failure	BD10-BD13	Phase 3	[2]
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Molecule Interaction Atlas

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References

1	Discovery of Aficamten (CK-274), a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy. J Med Chem. 2021 Oct 14;64(19):14142-14152.
2	CK-1827452, a sarcomere-directed cardiac myosin activator for acute and chronic heart disease. IDrugs. 2009 Apr;12(4):243-51.