Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT9XKUC)

DTT Name	Voltage-gated potassium channel Kv10.1 (KCNH1) DTT Info
Gene Name	KCNH1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
clofilium	DMQ37OP	Discovery agent	N.A.	Investigative	[1]
ICA-105574	DMS9H2P	Discovery agent	N.A.	Investigative	[2]
LY97241	DMTNVP4	Discovery agent	N.A.	Investigative	[1]
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Molecule Interaction Atlas

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References

1	Inhibition of hEAG1 and hERG1 potassium channels by clofilium and its tertiary analogue LY97241. Br J Pharmacol. 2003 Jan;138(1):161-71.
2	ICA-105574 interacts with a common binding site to elicit opposite effects on inactivation gating of EAG and ERG potassium channels. Mol Pharmacol. 2013 Apr;83(4):805-13.