Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTA1L39)

DTT Name	ICAM1 messenger RNA (ICAM1 mRNA) DTT Info
Gene Name	ICAM1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Discontinued Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 1570	DMJ9G23	Lleum inflammation	1A40.0	Approved	[1]
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1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Alicaforsen	DMQ509J	Lleum inflammation	1A40.0	Phase 3	[2]
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1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
INXC-ICAM1	DMODQW0	Transplant rejection	NE84	Terminated	[3]
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12 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
A-286982	DM98VFW	Discovery agent	N.A.	Investigative	[4]
Dehydropipernonaline	DMIOA9M	Discovery agent	N.A.	Investigative	[5]
ISIS 11158	DMX1OI8	Discovery agent	N.A.	Investigative	[6]
ISIS 11159	DM9V6FW	Discovery agent	N.A.	Investigative	[6]
ISIS 11665	DMYWINR	Discovery agent	N.A.	Investigative	[6]
ISIS 1931	DMBMQNI	Discovery agent	N.A.	Investigative	[1]
ISIS 2974	DM7K19L	Discovery agent	N.A.	Investigative	[1]
ISIS 3067	DMC9OL7	Discovery agent	N.A.	Investigative	[6]
ISIS 3224	DMAFEYG	Discovery agent	N.A.	Investigative	[6]
Pellitorin	DMYIWBD	Discovery agent	N.A.	Investigative	[5]
PIPERNONALINE	DMB3NZA	Discovery agent	N.A.	Investigative	[5]
PIPERROLEIN B	DMRVHWZ	Discovery agent	N.A.	Investigative	[5]
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⏷ Show the Full List of 12 Investigative Drug(s)

Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	US patent application no. 6,300,491, Oligonucleotide inhibition of cell adhesion.
2	Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2009).
3	ISIS 2302. INXC ICAM1, Oligo-TCS. Drugs R D. 1999 Jan;1(1):85-6.
4	Discovery of tetrahydroisoquinoline (THIQ) derivatives as potent and orally bioavailable LFA-1/ICAM-1 antagonists. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5269-73.
5	Alkamides from the fruits of Piper longum and Piper nigrum displaying potent cell adhesion inhibition. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4544-6.
6	US patent application no. 5,789,573, Antisense inhibition of ICAM-1, E-selectin, and CMV IE1/IE2.