Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTA7UJC)

• DTT Name: Alpha-1-antitrypsin (SERPINA1) DTT Info
• Gene Name: SERPINA1

Molecule-Related Drug & Molecule List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Glassia	DM83MOK	Emphysema	CA21	Approved	[1]
Zemaira	DMA5QPM	Emphysema	CA21	Approved	[2]

2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AGTC-0106	DMMKASG	Alpha-1 antitrypsin deficiency	5C5A	Phase 2	[3]
Igmesine	DMH97XA	Major depressive disorder	6A70.3	Phase 2	[4]

1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-Sulfhydryl-Ethanol	DMJBO3D	Discovery agent	N.A.	Investigative	[5]

References

• [1] Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5.
• [2] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services.
• [3] First gene therapy nears landmark European market authorization. Nat Biotechnol. 2012 Sep;30(9):807-9.
• [4] Emerging drugs for the treatment of chronic obstructive pulmonary disease. Expert Opin Emerg Drugs. 2006 May;11(2):275-91.
• [5] DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.