Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTAFJUD)

• DTT Name: Orotidine 5'-monophosphate decarboxylase (UMPS) DTT Info
• Gene Name: UMPS

Molecule-Related Drug & Molecule List

7 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
5-fluoro-6-amino-UMP	DM6QHIA	Discovery agent	N.A.	Investigative	[1]
5-fluoro-6-azido-UMP	DMZLJRS	Discovery agent	N.A.	Investigative	[1]
5-Fluoro-6-ethyluridine-5'-O-monophosphate	DMTAZ71	Discovery agent	N.A.	Investigative	[1]
5-fluoro-6-iodo-UMP	DM3LMIS	Discovery agent	N.A.	Investigative	[1]
6-Hydroxyuridine-5'-Phosphate	DMDMNQV	Discovery agent	N.A.	Investigative	[2]
Alpha-Phosphoribosylpyrophosphoric Acid	DMT6KI7	Discovery agent	N.A.	Investigative	[3]
Pyrazofurin	DMVJLSM	Discovery agent	N.A.	Investigative	[4]

References

• [1] Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents. J Med Chem. 2009 Mar 26;52(6):1648-58.
• [2] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [3] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
• [4] Molecular approaches for the treatment of hemorrhagic fever virus infections. Antiviral Res. 1993 Sep;22(1):45-75.