Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTAT87F)

DTT Name	Amylin receptor (IAPPR) DTT Info
Gene Name	CALCR-RAMP1/RAMP2/RAMP3

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Discontinued Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
DACRA 089	DM5TB76	Type 2 diabetes	5A11	Phase 1	[1]
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4 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Davalintide	DM9S3R8	Obesity	5B81	Discontinued in Phase 2	[2]
AC-253	DM704HO	Hypertension	BA00-BA04	Discontinued in Phase 1	[3]
AC-625	DMIJB68	Hypertension	BA00-BA04	Discontinued in Phase 1	[3]
AC-187	DM5IDAQ	Type-2 diabetes	5A11	Terminated	[4]
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Molecule Interaction Atlas

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References

1	A novel dual amylin and calcitonin receptor agonist, KBP-089, induces weight loss through a reduction in fat, but not lean mass, while improving food preference. Br J Pharmacol. 2017 Apr;174(7):591-602.
2	Davalintide (AC2307), a novel amylin-mimetic peptide: enhanced pharmacological properties over native amylin to reduce food intake and body weight. Int J Obes (Lond). 2010 Feb;34(2):385-95.
3	Biotechnology and Its Application in Pharmacy. Kulkarn. 2002. Page157.
4	Antagonist of the amylin receptor blocks beta-amyloid toxicity in rat cholinergic basal forebrain neurons. J Neurosci. 2004 Jun 16;24(24):5579-84.