Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTB18GJ)

• DTT Name: Proto-oncogene c-RAF (c-RAF) DTT Info
• Gene Name: RAF1

Molecule-Related Drug & Molecule List

4 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BGB-3245	DM1X3L0	Solid tumour/cancer	2A00-2F9Z	Phase 2	[1]
Semapimod	DMIJNLG	Autoimmune diabetes	5A10	Phase 2	[2]
Belvarafenib	DM0ZNAR	Solid tumour/cancer	2A00-2F9Z	Phase 1	[3]
GDC-5573	DMJA27W	Solid tumour/cancer	2A00-2F9Z	Phase 1	[4]

References

• [1] Clinical pipeline report, company report or official report of BeiGene.
• [2] Specific inhibition of c-Raf activity by semapimod induces clinical remission in severe Crohn's disease. J Immunol. 2005 Aug 15;175(4):2293-300.
• [3] Clinical pipeline report, company report or official report of Hanmi Pharmaceutical.
• [4] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)