Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTB30LE)

DTT Name Endoglin CD105 (ENG) DTT Info
Gene Name ENG

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
2 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
TRC105 DM1874J Angiosarcoma 2B56 Phase 3 [1]
ENV-105 DMC1SRK Non-small-cell lung cancer 2C25 Phase 1 [2]
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Molecule Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1 An open-label phase Ib dose-escalation study of TRC105 (anti-endoglin antibody) with bevacizumab in patients with advanced cancer. Clin Cancer Res. 2014 Dec 1;20(23):5918-26.
2 Monoclonal anti-endoglin antibody TRC105 (carotuximab) prevents hypercholesterolemia and hyperglycemia-induced endothelial dysfunction in human aortic endothelial cells. Front Med (Lausanne). 2022 Sep 7;9:845918.