Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTBJR4L)

DTT Name	Cyclin-dependent kinase 8 (CDK8) DTT Info
Gene Name	CDK8

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Preclinical Drug(s)

Clinical Trial Drug(s)

Patented Agent(s)

Investigative Drug(s)

Download the Complete Related Drug List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SEL120	DMHCUZV	Acute myeloid leukaemia	2A60	Phase 1	[1]
------------------------------------------------------------------------------------

2 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Macrocycle derivative 14	DMXSRPH	N. A.	N. A.	Patented	[2]
Tricyclic benzimidazole derivative 1	DM5SD9E	N. A.	N. A.	Patented	[2]
------------------------------------------------------------------------------------

1 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CCT251545	DMNA9KW	Colorectal cancer	2B91.Z	Preclinical	[3]
------------------------------------------------------------------------------------

2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Oxindole 16 (compound 3)	DMM5208	Discovery agent	N.A.	Investigative	[4]
Oxindole 94	DMPFD6Y	Pain	MG30-MG3Z	Investigative	[4]
------------------------------------------------------------------------------------

Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Clinical pipeline report, company report or official report of Ryvu Therapeutics.
2	Cyclin-dependent kinase inhibitors for cancer therapy: a patent review (2009 - 2014).Expert Opin Ther Pat. 2015;25(9):953-70.
3	Kinase inhibitors: the road ahead. Nat Rev Drug Discov. 2018 May;17(5):353-377.
4	Pharmacological inhibitors of cyclin-dependent kinases. Trends Pharmacol Sci. 2002 Sep;23(9):417-25.