Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTBMAOZ)

DTT Name	Regulatory protein unspecific (RGP) DTT Info
Gene Name	RGP

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Discontinued Drug(s)

Download the Complete Related Drug List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Teplizumab	DMZ3P6C	Type-1 diabetes	5A10	Approved	[1]
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2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Visilizumab	DMXYM1H	Graft-versus-host disease	4B24	Phase 3	[2]
NI-0401	DMEOLVP	Autoimmune diabetes	5A10	Phase 1/2	[3]
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1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
MEDI-500	DMT3B4G	Bone marrow transplantation	QB63.6	Terminated	[4]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Acquisition of regulatory function by human CD8(+) T cells treated with anti-CD3 antibody requires TNF. Eur J Immunol. 2010 Oct;40(10):2891-901.
2	Visilizumab induces apoptosis of mucosal T lymphocytes in ulcerative colitis through activation of caspase 3 and 8 dependent pathways. Clin Immunol. 2008 Jun;127(3):322-9.
3	Clinical pipeline report, company report or official report of NovImmune.
4	T10B9 (MEDI-500) mediated immunosuppression: studies on the mechanism of action. Clin Transplant. 1996 Dec;10(6 Pt 2):607-13.