Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTC97NF)

• DTT Name: TNFA messenger RNA (TNF mRNA) DTT Info
• Gene Name: TNF

Molecule-Related Drug & Molecule List

2 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 104838	DMURWPH	Crohn disease	DD70	Discontinued in Phase 2	[1]
PNU-282987	DMGDC36	Schizophrenia	6A20	Terminated	[2]

References

• [1] Design and development of antisense drugs. Expert Opin. Drug Discov. 2008 3(10):1189-1207.
• [2] Antisense oligonucleotide blockade of tumor necrosis factor-alpha in two murine models of colitis. J Pharmacol Exp Ther. 2003 Jan;304(1):411-24.