Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTCQ2E5)

• DTT Name: RIP2 messenger RNA (RIP2 mRNA) DTT Info
• UniProt ID: RIPK2_HUMAN
• Gene Name: RIPK2

Molecule-Related Drug & Molecule List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS-CRP	DMQDUG4	Cardiovascular disease	BA00-BE2Z	Phase 1	[1]

9 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 104211	DMPKQ61	Discovery agent	N.A.	Investigative	[2]
ISIS 104253	DMME8JP	Discovery agent	N.A.	Investigative	[2]
ISIS 104254	DMDEI9X	Discovery agent	N.A.	Investigative	[2]
ISIS 104255	DMAI5B8	Discovery agent	N.A.	Investigative	[2]
ISIS 104256	DMHUX9A	Discovery agent	N.A.	Investigative	[2]
ISIS 104257	DMSDCGV	Discovery agent	N.A.	Investigative	[2]
ISIS 104258	DMUC3L0	Discovery agent	N.A.	Investigative	[2]
NM-PP1	DMS8H5Q	Discovery agent	N.A.	Investigative	[1]
Src kinase inhibitor I	DMUZP9V	Discovery agent	N.A.	Investigative	[1]

References

• [1] The selectivity of protein kinase inhibitors: a further update. Biochem J. 2007 Dec 15;408(3):297-315.
• [2] US patent application no. 6,426,221, Antisense modulation of RIP2 expression.