Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTCSJBZ)

• DTT Name: GAR transformylase (GART) DTT Info
• Gene Name: GART

Molecule-Related Drug & Molecule List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AG2034	DMFU58V	Solid tumour/cancer	2A00-2F9Z	Phase 1	[1]

1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
DDATHF	DM6GWAC	Discovery agent	N.A.	Investigative	[2]

References

• [1] Phase I study of AG2034, a targeted GARFT inhibitor, administered once every 3 weeks. Cancer Chemother Pharmacol. 2000;45(5):423-7.
• [2] Rational design, synthesis, evaluation, and crystal structure of a potent inhibitor of human GAR Tfase: 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,... Biochemistry. 2003 May 27;42(20):6043-56.