Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTCW0KX)

• DTT Name: Glutaminase (GLS) DTT Info
• Gene Name: GLS

Molecule-Related Drug & Molecule List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CB-839	DM094UH	Breast cancer	2C60-2C65	Phase 2	[1]

12 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID30273516-Compound-1	DM52MKV	N. A.	N. A.	Patented	[2]
PMID30273516-Compound-12	DMIWEZH	N. A.	N. A.	Patented	[2]
PMID30273516-Compound-13	DMK9TJP	N. A.	N. A.	Patented	[2]
PMID30273516-Compound-14	DMURZHA	N. A.	N. A.	Patented	[2]
PMID30273516-Compound-15	DMSD647	N. A.	N. A.	Patented	[2]
PMID30273516-Compound-22a	DMVZA0U	N. A.	N. A.	Patented	[2]
PMID30273516-Compound-22b	DMZ5O3K	N. A.	N. A.	Patented	[2]
PMID30273516-Compound-37	DM8NBJV	N. A.	N. A.	Patented	[2]
PMID30273516-Compound-38	DMRPJBF	N. A.	N. A.	Patented	[2]
PMID30273516-Compound-39	DMBF3ZE	N. A.	N. A.	Patented	[2]
PMID30273516-Compound-40	DM5N8YJ	N. A.	N. A.	Patented	[2]
PMID30273516-Compound-41	DM5UBMJ	N. A.	N. A.	Patented	[2]

References

• [1] Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer. Mol Cancer Ther. 2014 Apr;13(4):890-901.
• [2] Glutaminase inhibitors: a patent review.Expert Opin Ther Pat. 2018 Nov;28(11):823-835.