Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTCZOF2)

DTT Name Pyruvate dehydrogenase kinase 1 (PDHK1) DTT Info
Gene Name PDK1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Approved Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
1 Approved Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dichloroacetate DMZ5Y1P Insulin-resistant disorder 5A44 Phase 4 [1]
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98 Patented Agent(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
1,2-dihydroindazolo[4,3-bc][1,5]benzoxazepine derivative 1 DMRFXMB Metastatic cancer 2D50-2E2Z Patented [2]
Benzimidazole and imidazopyridine derivative 1 DMIXERP Metastatic cancer 2D50-2E2Z Patented [2]
Benzonaphthyridine derivative 1 DMM9J34 Metastatic cancer 2D50-2E2Z Patented [2]
Benzonaphthyridine derivative 2 DMB74LZ Metastatic cancer 2D50-2E2Z Patented [2]
Bis-indolylmaleimide derivative 1 DMOR9ZA Metastatic cancer 2D50-2E2Z Patented [2]
Dibenzo [c,f]-[2,7]naphthyridine derivative 1 DMRM5I1 Metastatic cancer 2D50-2E2Z Patented [2]
Heteroaryl-carboxamide derivative 1 DMPRF1K Metastatic cancer 2D50-2E2Z Patented [2]
Heteroaryl-carboxamide derivative 10 DMVTARK Metastatic cancer 2D50-2E2Z Patented [2]
Heteroaryl-carboxamide derivative 2 DMGEFIW Metastatic cancer 2D50-2E2Z Patented [2]
Heteroaryl-carboxamide derivative 3 DMBGTNM Metastatic cancer 2D50-2E2Z Patented [2]
Heteroaryl-carboxamide derivative 4 DMHUIXR Metastatic cancer 2D50-2E2Z Patented [2]
Heteroaryl-carboxamide derivative 5 DMMX6V4 Metastatic cancer 2D50-2E2Z Patented [2]
Heteroaryl-carboxamide derivative 6 DM9IPDU Metastatic cancer 2D50-2E2Z Patented [2]
Heteroaryl-carboxamide derivative 7 DMOAYEV Metastatic cancer 2D50-2E2Z Patented [2]
Heteroaryl-carboxamide derivative 8 DMJTN91 Metastatic cancer 2D50-2E2Z Patented [2]
Heteroaryl-carboxamide derivative 9 DMI627Z Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 10 DMN580F Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 11 DMUOI92 Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 12 DMQJW9R Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 13 DMWOBHM Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 14 DMJ0WVR Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 15 DMWZNDO Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 16 DM6NJV7 Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 17 DMD1K7E Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 18 DMFUEDL Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 19 DMNG0WH Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 4 DM7VP8M Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 5 DMWJDEO Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 6 DM6HWN3 Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 7 DMU6LS4 Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 8 DMKPSIA Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic derivative 9 DMY4LB7 Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic-carboxamide derivative 1 DMA91IJ Metastatic cancer 2D50-2E2Z Patented [2]
Heterocyclic-carboxamide derivative 2 DMSQK50 Metastatic cancer 2D50-2E2Z Patented [2]
Imidazo quinoline derivative 1 DMGDMWA Metastatic cancer 2D50-2E2Z Patented [2]
Indazole derivative 1 DME8JTW Metastatic cancer 2D50-2E2Z Patented [2]
Indolinone derivative 1 DMTC129 Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-EP20041486488 DMDZT7Y Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-US20120277229 39(1.1) DMR4MSH Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-US20120277229 40(1.2) DMR3J9A Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-US20120277229 41(1.3) DM7V6E0 Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-US20120277229 44(1.4) DMUQ04C Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-US20120277229 45(1.5) DMEIA6Y Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-US20130053382 35(1-11) DMDHJMU Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-US20130053382 36(3-5) DM40FVN Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-US20130053382 37(4-6) DMY7Z85 Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-US20130053382 38(5-7) DMHLQ2T Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-WO2004087707 DM809AX Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-WO2006015124 DMV7PNF Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-WO2008005457 DMDMJYL Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-WO2008079988 DMKJ1HC Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-WO2008107444 DM8L5JR Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-WO2009153313 DMTP02Q Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-WO2010127754 DM37FDV Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-WO2011137219 35(1-11) DM3IZ0H Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-WO2011137219 36(3-5) DMAQHI5 Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-WO2011137219 37(4-6) DMSQ5J8 Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-WO2011137219 38(5-7) DM4NXBK Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-WO2012135799 42(1.4) DMSDRA4 Metastatic cancer 2D50-2E2Z Patented [2]
PMID25684022-Compound-WO2012135799 43(1.5) DMHI3O1 Metastatic cancer 2D50-2E2Z Patented [2]
Pyrazole derivative 61 DMO6M1Q Metastatic cancer 2D50-2E2Z Patented [2]
Pyrazolopyridines and imidazopyridine derivative 1 DMSR5FO Metastatic cancer 2D50-2E2Z Patented [2]
Pyridinone carboxamide derivative 1 DM3F4KS Metastatic cancer 2D50-2E2Z Patented [2]
Pyrido[4,3-d]pyrimidin-5(6H)-one derivative 1 DMOTGEK Metastatic cancer 2D50-2E2Z Patented [2]
Pyrimidine derivative 3 DMC3E8M Metastatic cancer 2D50-2E2Z Patented [2]
Pyrimidinone derivative 1 DM1I7Z6 Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 1 DMW62LX Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 10 DMWKI89 Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 11 DM0Q3HF Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 12 DMG0H73 Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 13 DMHQCEJ Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 14 DMMKNP7 Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 15 DMCH1DL Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 16 DMJQBVH Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 17 DMPMN92 Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 18 DM987MK Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 19 DMW59Q4 Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 2 DMLIRGM Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 20 DMORSH9 Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 21 DMTJBCG Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 22 DM6WTR2 Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 23 DMMO6JY Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 24 DMZ6YB0 Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 25 DMLRTFX Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 26 DM8DHZ4 Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 27 DMV30QO Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 28 DMGEIZV Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 29 DMCRVO5 Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 3 DMLRA3C Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 30 DMEOKCB Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 4 DMI3X14 Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 5 DM2H95E Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 6 DMWHCOE Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 7 DMLBK8V Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 8 DMVOTKN Metastatic cancer 2D50-2E2Z Patented [2]
Thiazole carboxamide derivative 9 DM5P04R Metastatic cancer 2D50-2E2Z Patented [2]
Thieno[3,2-c]pyridine-7-carboxamide derivative 1 DM1C8MA Metastatic cancer 2D50-2E2Z Patented [2]
Thieno[3,2-c]pyridine-7-carboxamide derivative 2 DMOWFA5 Metastatic cancer 2D50-2E2Z Patented [2]
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⏷ Show the Full List of 98 Patented Agent(s)
Molecule Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1 Comparison of Antitumor Effects of Combined and Separate Treatment with NO Synthase Inhibitor T1023 and PDK1 Inhibitor Dichloroacetate. Bull Exp Biol Med. 2019 Nov;168(1):92-94.
2 PDK1 disruptors and modulators: a patent review.Expert Opin Ther Pat. 2015 May;25(5):513-37.